Effects of Inverted Vision on Pointing and Grasping in Parabolic Flight

Not Applicable

• Conditions: Pointing Task; Gasping Task
• Interventions: Procedure: NORMAL VISON; Procedure: INVERTED VISION

• Registration Number: NCT02885844
• Lead Sponsor: University Hospital, Caen

Brief Summary

Parabolic flight is the only ground-based condition in which weightlessness (0G) can be created long enough for safely testing changes in human perception and behavior. In addition to the 0G period, parabolic flight generates equal duration periods of 1.8G, which present another unique opportunity to test the same responses to hypergravity and back to 1G.

Spatial orientation perception is a critical subsystem that is used by the central nervous system in the control of vehicles and other complex systems in a high-level integrative function. Evidence from space flight research demonstrates that spatial orientation is altered by the transitions in gravito-inertial force levels (Clément 2011; Clément \& Reschke 2008), transitions corresponding to mission phases particularly critical for crew safety and mission success. Accurate perception of self-in-space motion and self-motion relative to other objects is critical for successful operations that involve motor control e.g. doing an extra-vehicule activity or piloting the spacecraft. To date, there is only limited operational evidence that these alterations cause functional impacts on mission-critical operations and control capabilities. Immediately after space flight, most crewmembers have reported some degree of disorientation/perceptual illusion, often accompanied by nausea (or other symptoms of motion sickness), and frequently manifested by lack of coordination, particularly during locomotion The hypothesis is that alteration in sensorimotor performance induced by inverted vision is gravity depend: maximum alteration during hypergravity, intermediary alteration during normal gravity, minimal alteration during weightlessness.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-09
• Study First Submitted: 2016-03-08
• Status Verified: 2016-05
• Study First Submitted QC: 2016-08-26
• Last Update Submitted: 2016-08-26
• Study First Posted: 2016-09-01
• Last Update Posted: 2016-09-01
• Primary Completion: 2017-09
• Study Completion: 2017-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• Subjects will be staff member of the team or of other teams participating in the parabolic flight campaign
• Healthy volunteers (men or women)
• Aged from 21 to 65
• Affiliated to a Social Security system and, for non-French resident, holding a European Health Insurance Card (EHIC)
• Who accepted to take part in the study
• Who have given their written stated consent
• Who has passed a medical examination similar to a standard aviation medical examination for private pilot aptitude (JAR FCL3 Class 2 medical examination). There will be no additional test performed for subject selection.

Exclusion Criteria

• Person who took part in a previous biomedical research protocol, of which exclusion period is not terminated
• Person with medical history of oculomotor disorders
• Person with medical history of vestibular disorders
• Pregnant women

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
NORMAL VISION	NORMAL VISON	During normal vision trials, subject's field of view will be restricted by goggles without lenses (see below) in order to be equivalent to the inverted vision one.
INVERTED VISION	INVERTED VISION	inverted vision (upside down) using commercial off-the-shelf inverting prism goggles

Primary Outcome Measures

Name	Time	Method
Response time	During flight	the time between when the target or shape appears and the subject lifts their finger off of the screen

Secondary Outcome Measures

Name	Time	Method
Task duration	During flight	Only for the grasping task - the time between when the subject lifts their finger from the screen after having seen the shape, grasps the shape and touches the screen again. This will also be measured for the time between when the subject touches the screen, places the shape in the correct form fitter and touches the screen again
Accuracy	During flight	Only for the pointing task - the measured Euclidian distance from the target center to the coordinates of where the subject touched the screen.

Trial Locations

Locations (1)

CHU Caen; 🇫🇷 Caen, France