*REGISTRY - an observational study of the European Huntington's Disease Network (EHDN)*
- Conditions
- 10028037Huntington's disease
- Registration Number
- NL-OMON38177
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 800
.Individuals with clinical features of HD with a confirmatory family history of HD or with DNA testing results demonstrating the presence of the HD mutation (i.e. a CAG repeat expansion within the HD gene >35 on larger allele)
•Individuals without clinical features of HD with DNA testing result demonstrating presence of the HD mutation (i.e. CAG repeat expansion within the HD gene >35 on larger allele)
•First-degree relatives (i.e. parents, siblings, or children) of individuals with HD
•Second-degree relatives (i.e. grandparents and grandchildren) of participating individuals with HD
•Family members of participating individuals from category 1 or 2 who are know not to carry the HD mutation (e.g., spouses)
• Subjects who are unable to understand the study protocol or unable to give informed consent, and have no legal representative.
•Participants with choreic movement disorder other than HD.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>There is no fixed end of study as 'Registry' will take place during visits at<br /><br>the out-patient clinic of the department of Neurology or nursing home. The<br /><br>study is imbedded in the network that provides a platform for communication and<br /><br>exchange of views on HD and a basis for research. </p><br>
- Secondary Outcome Measures
Name Time Method <p>n.v.t.</p><br>