Altered Circadian Rhythm of Melatonin Secretion and Circadian Gene Expression in the Early Stage of Sepsis

Not Applicable

Completed

• Conditions: sepsis; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12612000494831
• Lead Sponsor: the First Affiliated Hospital of Wenzhou Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-05-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

critically ill patients (both sepsis and non-sepsis patients) admitted to the studied ICU in a university hospital

Exclusion Criteria

1. Patients with insomnia or mental illness; 2. Patients who had shift work before admission to the hospital; 3. Patients who received ß-blockers, melatonin or blocking agents of melatonin.

Study & Design

• Study Type: Observational
• Study Design: Not specified