Clinicopathological differences between right and left-sided T1 colorectal cancer
Not Applicable
- Conditions
- early colorectal cancer
- Registration Number
- JPRN-UMIN000032733
- Lead Sponsor
- Digestive Disease Center, Showa University Northern Yokohama Hospital
- Brief Summary
eft-sided T1 colorectal cancer(CRC) showed significantly higher rates of lymph node metastasis(LNM; left-sided 12.0% vs. right-sided 5.4%, P < 0.05) and lymphatic invasion (left-sided 32.7% vs. right-sided 23.2%, P < 0.05). Especially, the sigmoid colon and rectum showed higher rates of LNM than other locations. Patients with left-sided T1 CRC were younger than those with right-sided T1 CRC , as well as significantly lower rates of poorly differentiated carcinoma/mucinous carcinoma than right-sided T1 CRC.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 1142
Inclusion Criteria
Not provided
Exclusion Criteria
Cases of familial adenomatous polyposis, Lynch syndrome, ulcerative colitis, synchronous invasive carcinoma
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinicopathological features included patient age, sex, initial treatment, tumor size, morphology, invasion depth, histological grade, lymphatic invasion, vascular invasion, tumor budding, and lymph node metastasis.
- Secondary Outcome Measures
Name Time Method