Effect of anti-stain cream containing Ginger melasma

Phase 2

• Conditions: melasma.; Other melanin hyperpigmentation; L81.4

• Registration Number: IRCT20190210042676N8
• Lead Sponsor: Sina Trading Company

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

Cases of mild to moderate melasma (MGSC=1& 2)
General health
Signing the consent form for participation in the study

Exclusion Criteria

Documented allergies to components of cream
Use of topical lightening products like AHA ,BHA and retinoid component within 21 days prior to the study
Active skin disease at test area: rosacea, atrophy, acne and eczema
Pregnancy or lactating
Use of systemic corticosteroid and isotretinoin within 28 days prior to the study
History of laser treatment or dermabrasion or deep facialpeels within the past 3 months

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Modified melasma severity index. Timepoint: Before intervention, 6 and 12weeks after intervention and 3 months after stop using. Method of measurement: mMASI.

Secondary Outcome Measures

Name	Time	Method
Size and amount of skin spots. Timepoint: Before intervention, 6 and 12 weeks after using and 3 months after stop using. Method of measurement: Visio face.;Melanin content changes. Timepoint: Before intervention,6 and 12 weeks after using and 3 months after stop using. Method of measurement: mexameter.