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Three Month Safety and Efficacy Study of TRAVATAN® Versus Travoprost Ophthalmic Solution, 0.004%

Phase 3
Withdrawn
Conditions
Open Angle Glaucoma
Ocular Hypertension
Interventions
Registration Number
NCT01452009
Lead Sponsor
Alcon Research
Brief Summary

A multi-center, observer-masked, randomized, parallel group efficacy and safety study of TRAVATAN® versus a new formulation of Travoprost Ophthalmic Solution, 0.004%

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  1. Patients 18 years of age or older
  2. Either gender
  3. Any race/ethnicity
  4. Diagnosed with open-angle glaucoma (including patients with pseudoexfoliation and pigment dispersion) or ocular hypertension
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Exclusion Criteria
  1. Patients with any form of glaucoma other than open-angle glaucoma.
  2. Patients with a central cornea thickness greater than 620 μm
  3. Patients with Shaffer angle Grade < 2
  4. Patients with a cup/disc ratio greater than 0.80
  5. Patients with severe central visual field loss
  6. Best-Corrected Visual Acuity score worse than 55 ETDRS letters (20/80 Snellen equivalent)
  7. Chronic, recurrent or severe inflammatory eye disease
  8. Clinically significant or progressive retinal disease
  9. Other ocular pathology
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Travoprost Ophthalmic Solution, 0.004% (New Formulation)Travoprost Ophthalmic Solution, 0.004% (New Formulation)-
TRAVATAN®TRAVATAN®TRAVATAN® administered one drop once daily
Primary Outcome Measures
NameTimeMethod
Efficacy: mean IOP Efficacy as measured by mean IOP3 months
Secondary Outcome Measures
NameTimeMethod
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