The Baerveldt Implant.Corneal endothelial changes and tube position.

Completed

Conditions: Glaucoma

Registration Number: NL-OMON29065

Lead Sponsor: Het Oogziekenhuis Rotterdam (OZR)

Brief Summary: van Kleij J, Islamaj E, de Waard PWT, Vermeer KA, Lemij HG. The long-term postoperative effect of the Baerveldt glaucoma drainage device and trabeculectomy on the corneal endothelium. Acta Ophthalmol. 2020; 98(Suppl. S264): 20. [Abstract] van Kleij JM, Islamaj E, Vermeer KA, Lemij HG, de Waard PWT. The long-term postoperative effect of the Baerveldt glaucoma drainage device and of a trabeculectomy on the corneal endothelium. Acta Ophthalmol. 2022; 100(2): 212-217. PMID: 33629525

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 200

Inclusion Criteria

Age 18-75 years.
- Informed consent.
- Primary open-angle glaucoma, pseudoexfoliative glaucoma, or pigmentary glaucoma.

Exclusion Criteria

- History of intraocular surgery (i.e. strabismus surgery, tenon’s capsule or conjunctiva surgery, cataract surgery, cyclodestructive procedures etc.).
- History of ocular comorbidity (e.g. active uveitis, proliferative diabetic retinopathy).
- Pregnant or nursing women.
- Functionally monocular patients.
- Need for glaucoma surgery combined with other ocular procedures (i.e. cataract surgery, keratoplasty, or retinal surgery) or an anticipated need for additional ocular surgery.
- Best corrected visual acuity less than 0.1.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation between endothelial cell counts and tube position.

Secondary Outcome Measures

Name	Time	Method
- Pachymetry.<br>- Cell morphology (polymegathism, pleomorphism).<br>- Stromal changes.<br>- Tube length.<br>- Tube bevel.<br>- Corneal decompensation.<br>