Acute Kidney Injury as a Risk Factor for Myocardial Injury After Non Cardiac Surgery
- Conditions
- Acute Kidney Injury (AKI)
- Registration Number
- NCT05068167
- Lead Sponsor
- South Egypt Cancer Institute
- Brief Summary
The incidence of acute kidney injury (AKI) postoperatively has been identified to be 21.6% in adults and 18.3% in hospitalized individuals. Surgery-related AKI is a severe complication that is related not only to short-term complications as increases in mortality rate and development of cardiac complications but also with complications on long term, such as development of chronic kidney disease. A better understanding of the mechanism of this hypthesis will lead to better management of this complication.
- Detailed Description
A randomized blinded prospective study included 206patients who the candidate for major surgery at South Egypt Cancer Institute, Assiut University, Assiut, Egypt. From April 2018 till April 2019, a detailed history and careful examination, routine laboratory investigations were done, Baseline ECG was recorded 24hours before surgery and 48hours postoperative at ICU.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 240
- patients who were candidates for major non cardiac surgery
- chronic cardiac diseases (myocardial ischemia, heart failure), Active severe infection, pregnancy, chronic kidney disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Creatinine level every 12 hours Creatinine twice the baseline and urine output of fewer than 0.5 ml/kg per hour for 12 hours
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Alaa Ali Elzohry
🇪🇬Assuit, Egypt