Transradial Versus Transfemoral Arterial Access for Cerebral Angiography
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cerebral Angiography
- Sponsor
- Huashan Hospital
- Enrollment
- 748
- Locations
- 1
- Primary Endpoint
- the rate of successful diagnostic cerebral angiography
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
This study is multi-center, prospective, randomized (1:1) controlled trial designed to assess and compare the feasibility, safety and success of Transradial access (TRA) versus Transfemoral access (TFA) for diagnostic cerebral angiography.
Detailed Description
TFA is traditional approach for diagnostic cerebral angiography, which has several limitations and complications including pain and discomfort, retroperitoneal hemorrhage, pulmonary embolism and increased admissions. Transradial coronary angiography has demonstrated preponderance to circumvent this limitations and complications. However, this has not been studied in cerebral angiography. So, the purpose of this study is to assess and compare the feasibility, safety and success of TRA versus TFA for diagnostic cerebral angiography.
Investigators
Yuxiang Gu
Vice-president of Huashan Hospital west campus
Huashan Hospital
Eligibility Criteria
Inclusion Criteria
- •Age 18-90 years
- •Planned cerebral angiography for clinical reason
- •Eligible for either transfemoral or transradial approach
- •Accept to sign the written consent form (WCF)
Exclusion Criteria
- •Contraindications to cerebral angiography, such as allergy to iodine contrast agents and renal insufficiency (GFR \< 30 ml/min), etc.;
- •Failure to complete the follow-up as required by the protocol;
- •Urgency/Emergency procedure
- •Patients are participating in other clinical trials;
- •Being pregnant or plan to get pregnant in the short term.
Outcomes
Primary Outcomes
the rate of successful diagnostic cerebral angiography
Time Frame: 24 hours
the successful superselection of the aortic arch vessel without changing the arterial approach, with angiography results meeting diagnostic requirements
Secondary Outcomes
- the rate of successful accurate diagnosis(24 hours)
- the duration of angiography(During procedure)
- the duration of fluoroscopy(During procedure)
- the bedridden time(24 hours)
- the Visual Analogue Scale (VAS) score(24 hours)