Recearch for the role of the action of GLP-1 on normal glucose tolerance
Not Applicable
- Conditions
- ormal glucose tolerance
- Registration Number
- JPRN-UMIN000006858
- Lead Sponsor
- Division of Diabetes and Enocrinology Kobe University Graduate School of Medicine
- Brief Summary
Exenatide, but not liraglutide, markedly decelerated the peak of both plasma glucose and serum insulin levels during the OGTT, with the peaks of both glucose and insulin concentrations occurring at 150min after test initiation with exenatide compared with 30min in the control condition or with liraglutide. Exenatide and liraglutide reduced the area under the curve for plasma glucose levels during the OGTT by similar extents, whereas that for serum insulin levels was reduced only by exenatide.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 14
Inclusion Criteria
Not provided
Exclusion Criteria
ad lib blood glucose >= 200 mg/dl hypersensitivity for the drugs pregnancy or the possibility HbA1c >= 6.1% severe renal dysfunction and liver function Considering unsuitable for this research with other reasons
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method serum blood glucose,insulin,CPR,gulucagon which are obtain from OGTT Time:0,5,10,15,30,60,90,120,150,180 min
- Secondary Outcome Measures
Name Time Method