Open flap debridement and guided tissue regeneration after 20 years in infrabony defects

Not Applicable

• Conditions: K05.6; K05.5; Periodontal disease, unspecified; Other periodontal diseases

• Registration Number: DRKS00012863
• Lead Sponsor: Poliklinik für Parodontologie, Zentrum für Zahn-, Mund- und Kieferheilkunde der Johann Wolfgang-Goethe Universität Frankfurt am Main

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-08-03
• Study Completion: 2017-12-12
• Results First Posted: 2019-04-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

(1) Participation at the randomized clinical trials Guided tissue regeneration procedure with bioresorbable membranes versus conventional flap surgery in the treatment of infrabony periodontal defects (Ratka-Krüger at al. 2000) and Open flap debridement and guided tissue regeneration after 10 years in infrabony defects (Nickles et al. 2010),
(2) written informed consent

Exclusion Criteria

Disease or condition (e.g. valvular transplant), which triggers during the evaluation of different parameters (e.g. PPD and CAL) a transitory becteremia and is in need of an antibiotic prophylaxis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
(1) PAL-V gained 240 months after therapy, i.e. change of PAL-V from 12/120 to 240 months after therapy, (2) number of defects with attachment loss >2mm from 12/120 to 240 months, (3) tooth loss

Secondary Outcome Measures

Name	Time	Method
PBL-V-difference (bonesounding) between 12/120 and 240 months