Clinical Study of Qingfei Litan Decoction on Airway Mucus Hypersecretion in Stable Bronchiectasis

Not Applicable

• Conditions: Airway Mucus Hypersecretion in Bronchiectasis

• Registration Number: ITMCTR2200006062
• Lead Sponsor: Xiyuan Hospital, China Academy of Chinese Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

(1)Outpatients who met the diagnostic criteria for stable bronchiectasis;(2)o smoking within 1 year prior to enrollment, sputum >30 ml per day, and no acute exacerbations due to medical history and physical examination; (3) Aged 18-75 years; (4)TCM syndrome differentiation is phlegm and heat accumulation,Spleen and kidney deficiency; (5) Patients who have at least 3 acute exacerbations in the past year; (6) Those who are willing to follow the doctor's diagnosis and treatment arrangements and sign informed consent.

Exclusion Criteria

(1)Patients with dry bronchitis as the main manifestation of hemoptysis; (2) Those who have changed their condition within 4 weeks before enrollment;(3)Patients with severe hematopoietic system diseases, advanced malignant tumors, severe liver and kidney dysfunction;(4)Other circumstances that the investigator considers unfit for inclusion.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CASA-Q score;24-hour sputum volume;

Secondary Outcome Measures

Name	Time	Method
Mucin 5AC;Pulmonary function;Neutrophil elastase;erythrocyte sedimentation rate;Quantitative symptom score;tumor marke;Chest CT scan;C-reactive protein;The number of acute exacerbations of bronchiectasis;