Psychiatric Assessment of Patients With Dyssynergic Defecation and Its Impact on Their Quality of Life
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 148
- 试验地点
- 1
- 主要终点
- 1-Assess psychiatric disorders among patients with anorectal dyssynergia
研究概览
简要总结
Case control observational study conducted on DD patient and healthy control group.
- evaluate psychiatric disorders among patients with dyssynergic defecation
- evaluate the effect of delayed diagnosis of dysnergic defecation on the quality of the life
详细描述
Functional constipation is a functional bowel disorder that presents as persistently difficult, infrequent, or seemingly incomplete defecation.
Subjective and objective definitions of constipation include:
(1) straining, hard stools (hard, inspissated stool), unproductive calls ("want to but cannot"), infrequent stools, or incomplete evacuation. (2) <3 bowel movements per week, daily stool weight <35 g/day, or straining >25% of the time Dyssynergia defecation is common and affects up to one half of patients with chronic constipation. This acquired behavioral problem is due to the inability to coordinate the abdominal and pelvic floor muscles to evacuate stool The etiology of dyssynergic defecation is unclear however it was found that the problem began during childhood in 31% of patients, and after a particular event, such as pregnancy, trauma, or back injury in 29% of patients, and there was no cause in 40% of patients.
The first step in making a diagnosis of dyssynergic defecation is to exclude an underlying metabolic or pathologic disorder .A detailed history, prospective stool diaries, and a careful digital rectal examination will not only identify the nature of bowel dysfunction, but also raise the index of suspicion for this evacuation disorder. Anorectal physiology tests and balloon expulsion test are essential for a diagnosis. Newer techniques such as high-resolution manometry and magnetic resonance defecography can provide mechanistic insights.
. anorectal dyssynergia impact quality of life and cause psychiatric problems such as of anxiety, depression, obsessive compulsiveness, psychoticism, and somatization.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 15 Years 至 —(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients diagnosed as dyssynergia with anorectal manometric study
排除标准
- •patient with diabetes mellitus ,hypertension ,chronic kidney disease ,and chronic liver disease patients
- •patient with neurological disease
- •patient with thyroid disease
- •patient with past history of psychiatric disorders
- •patients with past or current medications or substance induced psychiatric disorders
结局指标
主要结局
1-Assess psychiatric disorders among patients with anorectal dyssynergia
时间窗: through study completion, an average of 1 year
Review the different types of psychiatric disorders in patients have diagnosed anorectal dyssynergia using SCID-5 ,anxiety and depression Hamilton score (from 0-4,zero refer to no symptoms ,4 refer to sever symptoms ), the summation of them show the type and severity of the condition
1-Assess psychiatric disorders among patients with dyssynergic defecation
时间窗: through study completion, an average of 1 year
Review the different types of psychiatric disorders in patients have diagnosed DD using SCID-5 ,anxiety and depression Hamilton score (from 0-4,zero refer to no symptoms ,4 refer to sever symptoms ), the summation of them show the type and severity of the condition
次要结局
- The impact of anorectal dyssynergia on the quality of the life(Through study completion, an average of 1 year)
- The impact of dyssynergia defecation on the quality of the life(Through study completion, an average of 1 year)
研究者
Dina Medhat Hussein
Principal Investigator
Assiut University
