A randomised comparison of laparoscopic myotomy and pneumatic dilatation for achalasia

niversity Health Network, Toronto (Canada)0 个研究点目标入组 100 人开始时间: 2005年7月28日最近更新: 2019年3月11日

试验速览

•1. Persons of either sex age groups 18 and up
•2. Clinical diagnosis of achalasia by a physician
•3. Manometric diagnosis of achalasia including both: incomplete relaxation of the lower oesophageal sphincter during swallowing (<80% of elevation over intragastric pressure) and absence of oesophageal peristalsis (peristalsis in <20% of initiated contractions)
•4. Facility with English, ability to complete English-language questionnaires

•1. Pseudoachalasia: oesophageal carcinoma; oesophageal stricture; previous oesophageal or gastric surgery; previous instrumentation of the lower oesophageal sphincter i.e. suture, polymer injection, silicone band
•2. Previous gastric or oesophageal surgery: fundoplication; Heller myotomy; gastric resection; vagotomy with or without gastric drainage
•3. Age 17 years or less
•4. Pregnancy
•5. Presence of severe comorbid illness: unstable angina; recent myocardial infarction (<6 months), cancer (except integumentary), unless free of disease for more than 5 years; end stage renal disease; previous stroke with cognitive, motor, speech, or swallowing deficit persisting longer than one month; severe respiratory disease; cognitive impairment

发起方

niversity Health Network, Toronto (Canada)