Dexamethasone and Analgesic Duration After Supraclavicular Brachial Plexus Blockade
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Duration of anesthesia
研究概览
简要总结
Patients undergoing surgery of the hand often are treated with a nerve block in the shoulder/neck area that provides anesthesia/numbing during surgery. Nerve blocks usually last for a few hours after surgery and provide pain relief for this period. It may be possible to extend the duration of anesthesia by using a steroid, which has anti-inflammtory properties. This study will compare the duration of the nerve block when dexamethasone (steroid) is added to the anesthetic injected around the nerve.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients having unilateral hand or forearm surgery under Supraclavicular brachial plexus blockade.
排除标准
- •Patients with a known history of hypersensitivity to local anesthetics and dexamethasone.
- •Contra-indication to regional anesthesia/ supraclavicular brachial plexus blockade e.g. bleeding diathesis, coagulopathy.
- •Peripheral neuropathy.
- •Peptic ulcer disease.
- •Diabetes Mellitus.
- •Inability to give informed consent.
研究组 & 干预措施
1
Dexamethasone 8mg added to routine local anesthetic during brachial plexus blockade.
干预措施: Dexamethasone (Drug)
1
Dexamethasone 8mg added to routine local anesthetic during brachial plexus blockade.
干预措施: Mepivicaine (Drug)
2
Routine anesthetic solution (30 cc 1.5% mepivicaine) used during brachial plexus blockade.
干预措施: Mepivicaine (Drug)
结局指标
主要结局
Duration of anesthesia
时间窗: hourly for first 24 hours; daily until discharge
次要结局
- Requirements for pain medications; complications(up to 3 months)