Evaluating the brain basis of a music intervention in autism

Completed

• Conditions: Autism Spectrum Disorder; Mental and Behavioural Disorders

• Registration Number: ISRCTN26821793
• Lead Sponsor: niversity of Montreal

Brief Summary

1. 2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/30352997/

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-07-18
• Study Completion: 2017-06-30
• Last Update Posted: 19 November 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Children aged 6-12 years
2. Diagnosis of Autism Spectrum Disorder
3. No co-morbid neurological disorder
4. No hearing impairment
5. No experience of music therapy in the 6 months preceding the start of the study

Exclusion Criteria

1. Co-morbid neurological condition
2. Metallic implant in body
3. Hearing impairment
4. Experience of music therapy in the 6 months preceding the start of the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Socio-communicative responsiveness (in the domains of Social Awareness, Social Cognition, Social Communication, Social Motivation, Restricted Interests and Repetitive Behavior) is measured using the Social Responsiveness Scale-2 at baseline and 12 weeks<br>2. Pragmatic language and communication skills are measured using the Children's Communication Checklist-2 at baseline and 12 weeks<br>3. Receptive vocabulary is measured using the Peabody Picture Vocabulary Test at baseline and 12 weeks<br>4. Functional brain connectivity was measured using resting-state functional MRI at baseline and at 12 weeks

Secondary Outcome Measures

Name	Time	Method
1. Family quality of life is measured using the Beach Family Quality of Life Scale at baseline and at 12 weeks<br>2. Gross and fine-motor skills are measured using the Motor skills subdomain of the Vineland Adaptive Behaviour Scales (II) at baseline and at 12 weeks<br>3. Inhibitory control is measured by the Flanker and Go-No Go task at baseline and at 12 weeks<br>4. Musical abilities are measured by the Montreal Battery of Evaluation of Musical Abilities at baseline and at 12 weeks