NCT05129202已完成不适用
Outcomes With Immune Checkpoint Inhibitor for Patients With Non-Small-Cell Lung Cancer and Stable Brain Metastases：A Retrospective Study
Hunan Province Tumor Hospital1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2017年11月3日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- PFS
研究概览
简要总结
Non-small cell lung cancer patients may have brain metastases at diagnosis. Patients with brain metastasis may contribute as poor prognosis factors. This trial aims to explore the efficacy and the safety of immune checkpoint inhibitors in non small cell lung cancer patients with initial brain metastasis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1.Diagnosed with advanced non-small cell lung cancer 2.Patients with brain metastasis
- •Treated with ICIs
排除标准
- •1.Patients with a clear driver mutation that can be targeted for first-line treatment
研究组 & 干预措施
immuntherapy
patients treated with immune checkpoint inhibitor monotherapy or combination therapy.
干预措施: immune therapy (Drug)
结局指标
主要结局
PFS
时间窗: November 2017- October 2021
progression free survival
ORR
时间窗: November 2017- October 2021
disease remission rate
次要结局
- OS(November 2017- October 2021)
研究者
Yongchang Zhang
Director, Head of Medical Oncology, Principal Investigator, Clinical Professor
Hunan Province Tumor Hospital
研究点 (1)
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