ACTRN12620000651987
招募中
2 期
Mega-dose Vitamin C for patients with septic shock: a pilot randomised controlled trial
Professor Rinaldo Bellomo0 个研究点目标入组 30 人2020年6月5日
概览
- 阶段
- 2 期
- 干预措施
- 未指定
- 疾病 / 适应症
- severe infection
- 发起方
- Professor Rinaldo Bellomo
- 入组人数
- 30
- 状态
- 招募中
- 最后更新
- 3年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Suspected or confirmed septic shock defined as an acute increase of:
- •\- equal to or greater than 2 sequential organ failure assessment (SOFA) points
- •\- need for continuous intravenous vassopressor therapy to maintain a mean arterial blood pressure of greater than 65 mmHg for greater than 2 hours and a serum lactate of greater than 2 mmol/L (despite adequate fluid resuscitation) within the previous 24 hours.
排除标准
- •Aged less than 18 years
- •Suspected or confirmed pregnancy
- •Do not resuscitate or do not intubate order
- •Death is deemed to be imminent or inevitable during this index hospital admission
- •Patients with know human immunodeficiency virus (HIV) infection
- •Patients with known glucose\-6 phosphate dehydrogenanse (G\-6PD) deficiency
- •Patients transferred from another intensive care unit or hospital with a diagnosis of septic shock for greater than 24 hours
- •Patient with known chronic iron overload due to iron storage and other diseases
- •Patient previously enrolled in this study
- •Patients with chronic haemodialysis or peritoneal dialysis.
结局指标
主要结局
未指定
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