Conventional Percutaneous surgery vs. Endoscopic Combined Intrarenal surgery for the treatment of large Kidney Stones
Not Applicable
- Conditions
- Kidney CalculiC12.777
- Registration Number
- RBR-7xzcmg7
- Lead Sponsor
- Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Adults aged 18 or over with kidney stones greater than 20 mm, candidates for PCNL in Barts position; Signed informed consent.
Exclusion Criteria
Impossibility to perform retrograde ureteroscopy (e.g., urinary reconstruction); Contraindications to PCNL (untreated urinary infection, uncorrected coagulopathy, ipsilateral kidney tumor, pregnancy); Concurrent ureteral stone or simultaneous bilateral approach; Uncontrolled comorbidities; Refusal to sign consent.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome 1: Stone free rate; acessed by CT scan, defined as no residual calculi or residual fragments up to 2mm; percentage rate in each group;Primary outcome 2: surgical success rate; acessed by CT scan, defined as residual fragments up to 4mm; percentage rate in each group
- Secondary Outcome Measures
Name Time Method Secondary outcome 1: access rate to all calyces; acessed by intraoperative nephroscopy; percentage rate in each group;Secondary outcome 2: intraoperative detection of residual fragments; acessed by intraoperative nephroscopy; percentage rate in each group;Secondary outcome 3: complication rate; acessed by the modified Clavien grading system at the end of follow up; percentage rate in each group;Secondary outcome 4: stone burden reduction; acessed by CT scan, comparing the stone volume at the begining and end of study; volume reduction (percentage) in each group