Monitoring Functional Capacity Through Heart Rate Variability Within the Multimodal Rehabilitation Program in Adult Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 490
- 试验地点
- 1
- 主要终点
- Correlation of HRV indices with functional capacity and frailty
研究概览
简要总结
This prospective, observational cohort study investigates heart rate variability (HRV) monitoring using the Analgesia Nociception Index (ANI) monitor in adult patients undergoing major surgery within a multimodal rehabilitation program. The objective is to correlate HRV indices with functional capacity, physiological reserve, and frailty during the prehabilitation phase.
详细描述
The study evaluates HRV using the ANI monitor to determine adaptation to training load, optimize analgesic and anesthetic dosing, and predict postoperative complications. The HRV indices of Energy (SDNN) and ANI (HFnu) are monitored at two points: the initial pre-anesthesia consultation and one week before surgery. Results will be compared with the 6-minute walk test, MUST nutrition screening scale, and clinical frailty and FRAIL scales.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients over 18 years of age
- •Scheduled for major adult surgery
- •Any ASA classification
- •Signed informed consent
排除标准
- •Urgent surgery
- •Severe cognitive impairment
- •Patient refusal to participate
- •Pediatric patients
- •Cardiac arrhythmia or atrial fibrillation
结局指标
主要结局
Correlation of HRV indices with functional capacity and frailty
时间窗: From initial pre-anesthesia consultation to 30 days postoperatively
Evaluation of the correlation between HRV indices (Energy and ANI) and current parameters used to assess functional capacity, physiological reserve, and frailty.
次要结局
- Reduction of postoperative complications(30 days postoperatively)
- Intraoperative decisions based on HRV(During the perioperative period)