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临床试验/CTRI/2025/08/092521
CTRI/2025/08/092521尚未招募4 期

Comparative evaluation of the amount, rate and type of tooth movement during canine retraction between healed versus recent upper premolar extraction site: a split mouth randomised controlled trial.

Priya Rajput1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2025年8月14日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
15
试验地点
1
主要终点
evaluation of amount, rate and type of tooth movement during canine retraction in a healed versus recent upper premolar extraction site

研究概览

简要总结

Orthodontic treatment duration depends on several factors like severity of malocclusion, treatment plan (extraction or non-extraction), patient compliance during treatment etc. Specially Extraction case therapy requires 18–24 months. In this treatment, extraction space closure consumes one-third to one-half of orthodontic treatment duration. In adult patients, lengthy orthodontic treatment is often accompanied with periodontal problems such as root resorption, alveolar bone loss, and gingival recession. Lengthy treatment is also responsible for poor patient compliance. Therefore, acceleration of orthodontic treatment becomes a good choice for Orthodontists for harnessing patients and doctor’s interest. Patients are keen for fast treatment due to treatment discomfort, social, and aesthetic concerns. To explore such treatment strategies many studies were conducted. Studies of tooth movement into a recent extraction site found accelerated tooth movement as compared to the site with healed socket. Thus, it was proposed that retraction of a tooth toward a recent extraction site is more advantageous compared to delayed retraction after extraction. Greater adjacent tooth tipping was reported when teeth were moved toward recent extraction sites as compared to healed extraction sites. The increased tipping on the recent extraction side was justified by the increased movement and the apical repositioning of the centre of resistance after adjacent tooth extraction. In contrast to these findings, another study, reported greater tooth retraction velocity into a healed socket than into a recent extraction socket. Also, similar tipping of teeth in both healed and recently extracted premolar sites have been found in some studies. A frequent complication associated with orthodontic space closure, after permanent tooth extraction, is development of a gingival cleft (GC), often also called invagination and infolding of gingiva. Gingival clefts have been reported to develop in about 35% to 100% of the extraction cases and are more frequent in the mandible. Some studies have suggested that gingival cleft development is a frequent finding during orthodontic space closure and seems to occur more frequently with early tooth movement initiation. On the contrary, other studies have found that the incidence of the gingival clefts did not vary in a statistically demonstrable fashion with the amount of time elapsing between tooth extraction and the initiation of orthodontic space closure. Thus, there is no conclusive data about how tooth movement varies in a recent extraction site as compared to a healed extraction site. Therefore, my study aims to evaluate the amount, rate and type of tooth movement during canine retraction in a recent versus healed extraction site of upper first premolar. This study will also be assessing gingival cleft formation in recent versus healed extraction site.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 30.00 Year(s)(—)
性别
All

入选标准

  • Patients of age ranging between 16-30 years requiring fixed mechanotherapy with extraction of upper first premolars as part of treatment plan.
  • Patients with aligned maxillary arches with mild to moderate crowding.
  • Patients with complete permanent dentition.

排除标准

  • 未提供

结局指标

主要结局

evaluation of amount, rate and type of tooth movement during canine retraction in a healed versus recent upper premolar extraction site

时间窗: at the initiation of canine retraction , at one month , two month and three month after initiation of canine retraction .

次要结局

  • evaluation of gingival cleft formation (if any) in both recent and delayed extraction groups(at the beginning of canine retraction and 3 months after initiation of canine tetraction.)

研究者

发起方
Priya Rajput
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Priya Rajput

Government Dental College and Hospital, Mumbai

研究点 (1)

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