Clinical Aspect of Erosive Pustular Dermatosis of the Leg
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- CHU de Reims
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Lesions location
研究概览
简要总结
Erosive pustular dermatosis of the leg is a fairlyrecent clinical entity that was described the first time in 1987.
Diagnosis of erosive pustular dermatosis of the leg is made on clinical grounds. It presents as non-follicular pustules of variable size and numbers that rapidly give way to erosions and crusts on one or both legs, and which are found in particular on the anterior aspect of the middle third of the leg (. The lesions are of chronic progression, despite topical therapy. Erosive pustular dermatosis of the leg is seen in elderly patients, mainly female, and may be associated with chronic venous insufficiency or cutaneous atrophy. In the absence of specific criteria and because of the existence of misleading clinical forms, diagnosis is based upon exclusion.
详细描述
The primary objective of this investigation was to describe the different clinical aspects of cases of Erosive pustular dermatosis of the leg.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •non-follicular pustules and multiple erosions on one or both legs showing no evidence of improvement after application of compression in the event of clinical signs of chronic venous insufficiency and showing no improvement following treatment with local and/or systemic antibacterial therapy, fungal samples from the pustules negative on direct examination, negative direct immunofluorescence results for biopsy samples (taken from around the lesion)
排除标准
- •age < 18 years old
结局指标
主要结局
Lesions location
时间窗: Day 0
Anterior or posterior leg face
number of lesions
时间窗: Day 0
Less than 10 erosions, between 10 and 50 erosions and more than 50 erosions
Presence of chronic venous insufficiency
时间窗: Day 0
Diagnosis based on the CEAP 2004 Score (Eklöf B, Rutherford RB, Bergan JJ, Carpentier PH, GloviczkiP, Kistner RL, et al. Revision of the CEAP classification forchronic venous disorders: consensus statement. J Vasc Surg2004;40:1248-52)
次要结局
未报告次要终点
