MedPath

Teneligliptin-Glimepiride DDI Study

Phase 1
Completed
Conditions
Diabetes Mellitus
Interventions
Drug: Teneligliptin+Glimepiride
Registration Number
NCT03009513
Lead Sponsor
Handok Inc.
Brief Summary

An open label, one sequence study to investigate the pharmacokinetic drug interaction between Teneligliptin and Glimepiride in healthy male subjects

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
26
Inclusion Criteria
  1. Healthy male adult aged 20 to 45 years
  2. Body weight ≥ 50kg, and BMI between 18 and 29 kg/m2 at screening
  3. Subject who agrees to use a medically acceptable double-barrier method of contraception and not to donate sperms from the first dose until 2 months after the last dose.
  4. Subject who was given, and fully understood, the information about the study, and has provided voluntary written informed consent to participate in the study and agreed to comply with the study requirements.
Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
single armTeneligliptin+Glimepiride-
Primary Outcome Measures
NameTimeMethod
Peak Plasma Concentration (Cmax)24hr
Area under the plasma concentration versus time curve (AUC)24hr
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath