Growth Hormone 120 Minutes Following a Single Low-dose of Amino Acids in Healthy Subjects.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Change From Baseline of Growth Hormone
研究概览
简要总结
The purpose of the study is to confirm the results of a prior study that demonstrated pills containing two amino acids which are in foods increased growth hormone and insulin-like growth factor-1.
详细描述
Oral supplementation with a key combination of derivatives that has been shown to increase human growth hormone in healthy volunteers peaking at 90 minutes and IGF-1 at 8 hours post-administration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •healthy males and healthy females
- •Between 18 and 70 years
排除标准
- •Pregnant or nursing
- •Taking any chronic medication including birth control pills.
研究组 & 干预措施
amino acid supplement
supplements with the proprietary amino acid derivative blend.
干预措施: Amino acid supplement (Drug)
Placebo
Non-Active
干预措施: Placebo (Drug)
结局指标
主要结局
Change From Baseline of Growth Hormone
时间窗: 0-120 minutes, at Baseline and post dose, week 1 and week 3
Measure human growth hormone at times 0-120 minutes on two occasions about one week apart. On one occasion, the proprietary amino acid derivative blend will be given orally at time 0 in capsule form, and on the other occasion the capsules will contain no amino acids.
Area Under the Curve of Growth Hormone Over Baseline
时间窗: 0-120 minutes, at Baseline and post dose, week 1 and week 3
Measure human growth hormone at times 0-120 minutes on two occasions about one week apart. On one occasion, the proprietary amino acid derivative blend will be given orally at time 0 in capsule form, and on the other occasion the capsules will contain no amino acids.
次要结局
- Insulin-like Growth Factor 1(8 hours following administration)
研究者
Frank Greenway
Principal Investigator
Pennington Biomedical Research Center