Assessment of the response to oral desensitization in patients with milk allergy

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo0 个研究点开始时间: 2022年3月26日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Patients over three years old; diagnosis of persistent IgE-mediated cows milk allergy with compatible and reproducible immediate symptoms for less than one year or recent positive oral test (one year interval); severe cows milk allergy: as reported or recorded in the medical record of anaphylaxis history; specific IgE for milk, alpha-lactalbumin, beta-lactoglobulin or casein positive by the ImmunoCAP method; positive prick test with a diameter greater than or equal to three millimeters of the negative control for milk in natura; and possess self-injecting adrenaline

•Patient diagnosed with cows milk allergy with some degree of tolerance; patient with non-IgE-mediated cows milk allergy; patient with eosinophilic esophagitis prior to immunotherapy; patients with uncontrolled asthma; patients with cardiovascular diseases or other diseases and therapies that contraindicated the use of adrenaline; patients with serious systemic diseases such as autoimmune diseases and malignant neoplasms; and patients and/or caregivers who have difficulty understanding the purpose of treatment, following treatment instructions, and recognizing and treating adverse reactions (not familiar with the action plan)

发起方

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo