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Clinical Trials/NCT03845283
NCT03845283
Active, not recruiting
Not Applicable

Optimization and Evaluation of a Tailored Behavioral eHealth/mHealth Weight Loss Intervention for Cardiac Rehabilitation Patients Using the Multiphase Optimization Strategy

The Miriam Hospital1 site in 1 country198 target enrollmentMay 2, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiovascular Diseases
Sponsor
The Miriam Hospital
Enrollment
198
Locations
1
Primary Endpoint
Weight Change
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

Cardiovascular disease (CVD) is the leading cause of death in the United States. Cardiac rehabilitation (CR) is the main treatment for heart attacks and other types of CVD. It is based on science, it saves money, and it is widely-available. Each session (of which there are a few each week for 3 months) combines supervised exercise and instruction. The goals are to improve overall health and reduce cardiovascular risk in individuals with established CVD. CR produces almost no weight loss (WL); if a person has excess weight while in CR (the majority of participants have overweight or obesity), losing weight could really reduce their risk of having another heart attack. The best treatment available for weight loss, in-person behavioral weight loss interventions (BWLs), produce enough WL that they improve health and disease risk/severity. However, in-person BWLs are too much work to be carried out in CR. A previous fully automated 3-month online program, Rx Weight Loss (RxWL), produced good WL in many different settings. Dr. Goldstein aims to tailor RxWL for use in CR. The study will use the Multiphase Optimization Strategy (MOST) to test innovative eHealth/mHealth intervention components that might work well for people when combined with RxWL. The study will include 160 patients (each randomized to receive 0-4 of the components). The components are: (a) a Fitbit with a goal-setting program; (b) a bite counting device; (c) a Web-based virtual reality (VR) intervention ; and (d) virtual meetings. By the 6-month follow-up, the investigators will know if any of those 4 components helped people lose more weight. If a component produced at least 2% WL, it will be studied further by being included in a new intervention to be tested in the next study.

Registry
clinicaltrials.gov
Start Date
May 2, 2019
End Date
September 1, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • currently a participant in The Miriam Hospital's or Newport Hospital's outpatient phase II cardiac rehabilitation program
  • medical clearance to participate by the Medical Director
  • a body mass index (BMI) between 27-45 kg/m2
  • must have a personal computer in their home with internet access
  • must read and understand English
  • willing to use technology to assist with weight loss

Exclusion Criteria

  • currently in another weight loss program
  • taking weight loss medication
  • weight loss of ≥ 5% of body weight in the past 6 months
  • currently pregnant, lactating, \< 6 months post-partum, or plans to become pregnant during the next year
  • report of loss of consciousness on the Physical Activity Readiness Questionnaire
  • New York Heart Association Class IV heart failure
  • heart transplant in the last 3 months
  • receipt of left ventricular assist device in the last 2 months
  • a physician diagnosis of dementia
  • a physician prescription for 24 hours of oxygen therapy daily

Outcomes

Primary Outcomes

Weight Change

Time Frame: At baseline, 3-, and 6-months after initiating the program

The difference between initial weight and weight at the follow-up assessments. Patients will be asked to step on a scale at the assessment clinic.

Secondary Outcomes

  • Structured Weekly Moderate-to-Vigorous Physical Activity Minutes(At baseline, 3-, and 6-months after initiating the program)
  • Number of Bites(At baseline, 3-, and 6-months after initiating the program)
  • Weight Control Practices(At baseline, 3-, and 6-months after initiating the program)
  • Weight Loss Self-Efficacy: Weight Efficacy Lifestyle Questionnaire(At baseline, 3-, and 6-months after initiating the program)

Study Sites (1)

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