COMPARISON OF EFFICACY AND SAFETY OF ORAL BILASTINE WITH ORAL CETIRIZINE IN ALLERGIC RHINITIS-AN OPEN LABEL RANDOMISED CONTROLLED TRIAL

Thesis Protocol titled COMPARISON OF EFFICACY AND SAFETY OF ORAL BILASTINE WITH ORAL CETIRIZINE IN ALLERGIC RHINITIS AN OPEN LABEL RANDOMISED CONTROLLED TRIAL will be done in North East India in department of pharmacology and otorhinolaryngology to compare the efficacy and safety of the most commonly used drugs for treamtents of Allergic Rhinitis that is oral bilastine and cetirizine Among2nd generation antihistaminic as an antiallergic only cetirizine has been included in NLEM 2022 But it has been reported that it has some adverse effect like headache sedation and dizziness so if a drug with better efficacy and safety profile can be identified through comparative studies it will be of great help for the patients suffering from Allergic Rhinitis hence this study has been taken up for comparison of the two molecules study period is of 78weeks, 70 weeks for data collection and sample size    Case-Record Form containing History general physical examination systemic & local examination along with total nasal & non nasal symptoms score will be used  the study tool Consent from particapnts will be taken Data will be entered & analysed in the SPSS version  statistical software