ISRCTN11629138已完成不适用
European Pharmacogenetics of Anticoagulant Therapy
niversity of Liverpool (UK)0 个研究点目标入组 706 人开始时间: 2010年10月29日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 706
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Patients with either venous thromboembolism (VTE) or atrial fibrillation (AF) requiring coumarin therapy for at least 12 weeks and a target International Normalised Ratio (INR) in the low intensity range (INR range 2 - 3)
- •2. Aged greater than or equal to 18 years, either sex
- •3. Ability to attend scheduled visits
- •4. Signed informed consent
排除标准
- •1. Presence of a mechanical heart valve
- •2. Severe cognitive impairment which affects adherence to therapy as judged by the responsible physician
- •3. Known genotype CYP2C9 or VKORC1 at start of the study
- •4. Previous or current treatment with any coumarin (maximum one dose allowed)
- •5. Pregnancy or lactation
- •6. Non-eligible subject according to the treating physician
- •7. A blood transfusion within the last two weeks or bone marrow transplantation at any time
研究者
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