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Clinical Trials/NCT00314171
NCT00314171
Completed
Phase 3

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Alcon Research0 sites437 target enrollmentOctober 2005
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ConditionsOpen-angle GlaucomaOcular Hypertension
InterventionsBrinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspensionDorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)
DrugsBrinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspensionDorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)

Overview

Phase
Phase 3
Intervention
Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension
Conditions
Open-angle Glaucoma
Sponsor
Alcon Research
Enrollment
437
Primary Endpoint
Mean IOP
Status
Completed
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSimilar Trials

Overview

Brief Summary

The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.

Registry
clinicaltrials.gov
Start Date
October 2005
End Date
August 2007
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •18 years or older
  • •Diagnosis of open-angle glaucoma or ocular hypertension
  • •Other protocol-defined inclusion criteria may apply

Exclusion Criteria

  • •Other protocol-defined exclusion criteria may apply

Arms & Interventions

Brinzolamide + Timolol

Intervention: Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension

Dorzolamide + Timolol

Intervention: Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)

Outcomes

Primary Outcomes

Mean IOP

Secondary Outcomes

  • Percent patients with IOP < 18 mmHg

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