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临床试验/NCT06505499
NCT06505499已完成不适用

Gait Profile Score in Children With Cerebral Palsy (CP): Influence of the CP Type, Treatment With Botulinum Injection and Multilevel Surgery

Centre Hospitalier Universitaire de Saint Etienne1 个研究点 分布在 1 个国家目标入组 51 人开始时间: 2024年3月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
51
试验地点
1
主要终点
Degrees of Gait Profile Score overall

研究概览

简要总结

Instrumented three dimensional gait analysis (3DGA) permits to record spatial, temporal, kinetics, kinematics and electromyographic (EMG) parameters in order to understand gait impairment in children and teenagers with cerebral palsy (CP). Nowadays, single-event multilevel surgery in subjects with CP cannot be performed without 3DGA. However, interpretation of multiple and interdependent data remains complex for the clinician. To address this issue, gait statistical index have been developed to give a single measure of the quality of the gait pattern. Among actual index, the Gait Profile Score (GPS), developed by Baker et al (2009), measure the deviation of kinematics parameters from a controlled dataset. The GPS can be divided in nine Gait Variable Score (GVS), corresponding to major lower limb joints: the MAP (Movement Analysis Profile). Many studies have reported the interest of the GPS to analysis gait of subjects with CP: good inter-session reliability, predictor of postoperative kinematic improvement, minimal clinical threshold calculated at 1.6°, significant relationship with clinical data (joint contractures), and sensibility to change after a single-event multilevel surgery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
6 Years 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Etiology of cerebral palsy
  • Unilateral, bilateral, triplegic or quadriplegic forms of cerebral palsy.
  • 6 to 18 years old
  • GMFCS (Gross Motor Function Classification System) I to III
  • Instrumented gait analysis of the laboratory of St-Etienne
  • Absence of botulinum toxin injection or serial casting in the three months after a first instrumented gait analysis.

排除标准

  • Etiology others than cerebral palsy as defined classically (ex: ischemic infarcts in a child older than two years).
  • Previous surgery in lower-limb.

结局指标

主要结局

Degrees of Gait Profile Score overall

时间窗: Day 1

Analyze Degrees of Gait Profile Score overall

次要结局

  • Gait Profile Score left(Year 2)
  • Gait Profile Score right(Month 2)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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