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Clinical Trials/NCT01021046
NCT01021046
Completed
Not Applicable

Deep Anterior Lamellar Keratoplasty Using Acellular Corneal Tissue Promotes Corneal Allograft Survival in High Risk Patients

Wenzhou Medical University1 site in 1 country78 target enrollmentDecember 2006
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ConditionsGlycerin Cryopreserved Acellular Corneal TissueDeep Anterior Lamellar KeratoplastyHigh Risk Keratoplasty

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Glycerin Cryopreserved Acellular Corneal Tissue
Sponsor
Wenzhou Medical University
Enrollment
78
Locations
1
Primary Endpoint
rejection
Status
Completed
Last Updated
15 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is to study whether deep anterior lamellar keratoplasty (DALK) using acellular tissue will promote corneal graft survival in high risk patients.

Registry
clinicaltrials.gov
Start Date
December 2006
End Date
July 2010
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •severe bacterial keratitis
  • •Herpes simplex keratitis
  • •severe fungal keratitis
  • •partial limbal deficiency after chemical burn

Exclusion Criteria

  • •posterior stroma involved in severe bacterial and fungal keratitis
  • •glaucoma or intraocular pressure greater than 21 mmHg
  • •amblyopia
  • •retinal abnormalities
  • •patients with severe systemic diseases not good for ocular surgery

Outcomes

Primary Outcomes

rejection

Secondary Outcomes

  • laser scanning in vivo confocal microscopy

Study Sites (1)

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