Observational Crossover Study Comparing Oxygenation and Ventilation Using Biphasic CPAP (SiPAP) Versus CPAP to Treat Respiratory Distress in Low Birth Weight Infants

Children's Hospitals and Clinics of Minnesota1 个研究点分布在 1 个国家目标入组 20 人开始时间: 2010年1月最近更新: 2012年6月22日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Children's Hospitals and Clinics of Minnesota
入组人数: 20
试验地点: 1

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

Investigation of effects of SiPAP versus NCPAP on oxygenation and ventilation in LBW infants with respiratory distress. Our hypothesis is that the LBW infants will achieve the same level of oxygenation and improved ventilation when being treated with SiPAP as compared to NCPAP.

研究设计

研究类型: Observational
观察模型: Case Crossover
时间视角: Prospective

入排标准

性别: All
接受健康志愿者: 否

入选标准

•LBW infant (birth weight <2500 grams)
•Currently on nasal CPAP
•Use of nasal CPAP for >24 hours prior to study initiation
•If history of intubation with mechanical ventilation, patient will be extubated >24 hours prior to study initiation
•FiO2 requirement of 25-50%

排除标准

•FiO2 requirement >0.5
•Congenital defects/deformities of the head, pulmonary or cardiovascular systems
•Chromosomal abnormalities/genetic syndromes
•Active medical treatment for symptomatic PDA
•Active medical treatment for culture proven sepsis
•Within 24 hours of invasive surgical procedure

研究者

发起方

Children's Hospitals and Clinics of Minnesota

申办方类型

Other

责任方

Principal Investigator

主要研究者

Andrea Lampland

Neonatologist

Children's Hospitals and Clinics of Minnesota

研究点 (1)

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