NCT00312312Unknown不适用
Does Specific Immunotherapy Possess Immunomodulative Effects at the Bronchial Mucosa Level Among Adults With Atopic Diseases?
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Sputum examination
研究概览
简要总结
The purpose of this study is to evaluate the immunomodulatory effect of treatment of allergic rhinitis symptoms with specific immunotherapy by measurement of pulmonary inflammatory markers, and among others, exhaled nitric oxide.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-45 years old
- •Skin prick test or RAS test and physical examination conclude that the patient will have a beneficial effect from specific immunotherapy
排除标准
- •Other diseases except atopic disease
- •Pregnancy
结局指标
主要结局
Sputum examination
Condensation of exhaled air
Skin prick test
Spirometry
Methacholine provocation of the pulmonary system
Exhaled nitric oxide
Immunoglobulin E (IgE) status
次要结局
- Questionnaire
研究者
研究点 (2)
Loading locations...
相似试验
已完成
2 期
Immunomodulation of E.Coli Nissle 1917 in Patients With Grass Pollen RhinoconjunctivitisRhinoconjunctivitisNCT01013259Charite University, Berlin, Germany34
招募中
不适用
Monitoring Allergen Immunotherapy in Allergic RhinitisImmunotherapyRhinitis, AllergicTreatment OutcomeNCT05621356Rijnstate Hospital25
已完成
不适用
Mechanisms of Allergen ImmunotherapyHypersensitivityAsthmaNCT00001910National Institute of Allergy and Infectious Diseases (NIAID)50
已完成
4 期
The Effect of Allergen Immunotherapy on Anti-viral Immunity in Patients With Allergic AsthmaAllergic Asthma Due to Dermatophagoides PteronyssinusNCT04100902Bispebjerg Hospital39
Unknown
不适用
Immunological Mechanisms of Allergy ImmunotherapyAllergy DesensitizationNCT01914029Rambam Health Care Campus70