Study of post operative sore throat, hoarseness of voice and cough after nebulization with ketamine and magnesium sulphate in patients undergoing general anaesthesia.

Phase 3

• Conditions: Health Condition 1: O- Medical and Surgical

• Registration Number: CTRI/2024/03/063567
• Lead Sponsor: JLN Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients between 18- 60 years of either sex

Undergoing surgeries under general anaesthesia in supine position

Duration of surgery upto 2hours

ASA physical status -I & II

Exclusion Criteria

Age- <18 and >60 yrs

ASA physical status III & above

Mallampatti grade >2

Any psychiatric disorder and history of epilepsy

Neurological patients with raised Intracranial pressure

Patients with known coronary artery disease,old myocardial infarction and ischemic heart disease

Pregnancy

Patients sensitive or allergic to study drugs

History of pre operative sore throat, oral surgeries, asthma ,chronic obstructive pulmonary disease, head and neck surgeries

Recent non steroidal drugs medication

Anticipated difficult intubation

Patients those who will require >2attempts at intubation

Patients and/ or his/her legally acceptable representative not willing to provide their voluntary written informed consent for participation in the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence and severity of sore throat, hoarseness of voice and coughTimepoint: 24 hours postoperative period

Secondary Outcome Measures

Name	Time	Method
haemodynamic changes, side effectsTimepoint: 24 hours post operative period