The Measurement of Nocturnal Hypokinesia in Parkinson's Disease (PD) Patient Compared With Spouse by Wearable Sensors
试验速览
- 阶段
- 不适用
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- the velocity of axial movement of Parkinson's disease patients compare to their spouses defined by accelerometer
研究概览
简要总结
To quantitative measurement of nocturnal hypokinesia of Parkinson's disease patients compares with their spouses by using multisite accelerometers for 1 night at their home. To determine whether the nocturnal movement of Parkinson's disease patients less than normal elderly people or not.
详细描述
To quantify the severity of nocturnal akinesia, the nocturnal akinesia dystonia and cramp score (NADCS) and Unified Parkinson's Disease Rating Scale (UPDRS) were recorded in the patient group and also details of demographic data, history and physical examinations were included. The patients and spouses wore the 3-axis (x,y,z) accelerometers at bilateral wrists, bilateral ankles, and trunk for 1 night at their home. The 5-minute periods after going to bed and before waking up in the morning were excluded from the analysis. The definition of movement of the trunk is a change of 15 degrees from the previous position and sustained for 5 minutes in any axis. The movement of limbs is defined as a change of 15 degrees from the previous position and sustained for 2 minutes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Parkinson's disease patients who met the criteria diagnosis of United Kingdom Parkinson's Disease Society Brain Bank (UKPDSBB) with their spouses which age difference less than 10 years.
排除标准
- •patients and/or spouses who were bed ridden,
- •a history of other neurological diseases or other muscle and joint diseases,
- •no history of hypnotic drug use
结局指标
主要结局
the velocity of axial movement of Parkinson's disease patients compare to their spouses defined by accelerometer
时间窗: one year
the acceleration of axial movement of Parkinson's disease patients compare to their spouses by accelerometer
时间窗: one year
the number of axial movement of Parkinson's disease patients compare to their spouses defined by accelerometer
时间窗: one year
次要结局
- The correlations between nocturnal hypokinesia parameter (number of axial movement) and severity of Parkinson's disease.(one year)
- The correlations between nocturnal hypokinesia parameter (degree of axial movement) and severity of Parkinson's disease.(one year)
- The correlations between nocturnal hypokinesia parameter (velocity of axial movement) and severity of Parkinson's disease.(one year)
研究者
Jirada Sringean
Dr
Chulalongkorn University