Reducing Hospital Readmissions in Patients With Depressive Symptoms
- Conditions
- Depression
- Interventions
- Other: RED-D Care Management
- Registration Number
- NCT01840826
- Lead Sponsor
- Boston Medical Center
- Brief Summary
Project Re-Engineered Discharge (Project RED) has previously demonstrated that patients who received the RED were 30% less likely than patients receiving usual care to access inpatient or emergency services within 30 days of discharge. In this project, the investigators add a new dimension to RED by integrating screening, referral and treatment for depression into the original RED intervention and determining if this enhanced intervention increases the effectiveness of RED in preventing readmissions and controlling costs in the 180 days after discharge for patients with signs of depression.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 709
- Over 18 years of age
- Admitted to any Boston Medical Center inpatient service or for observation
- Screen positive for depressive symptoms (Patient Health Questionnaire - 2 >/= 3)
- Speaks English with health care providers
- Has access to a telephone
- Live in the Boston area and don't plan on leaving the Boston area for more than 2 weeks in the next 6 months
- Screen positive for depressive symptoms (PHQ -9 >/= 10)
- Has plans for inpatient rehabilitation, nursing home, or other institutional settings after discharge.
- Suicidal precautions
- Sickle Cell Crisis (SCC)
- Alcohol and/or drug dependence
- Diagnosis of Bipolar Disorder, Schizophrenia or other Psychotic Disorder
- In police custody
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description RED-D Care Management RED-D Care Management Patients randomized to receive the Intervention work with a RED-D Care Manager post-discharge. The Care Manager meets with the patient in the hospital, prior to discharge, and post-discharge via weekly phone calls. Patients have access to a range of treatment options, overseen by the Care Manager, including: (1) medication; (2) cognitive behavioral therapy (CBT); (3) complementary and alternative medicine (CAM) information and referral; (4) Self-help, such as reading a book, making a change in diet and/or exercise in order to improve mood; (5) active surveillance; and (6) any combination of 1, 2, 3, 4 \& 5.
- Primary Outcome Measures
Name Time Method All-cause readmission rates 30 days and 90 days post-discharge from hospital at index admission The primary hypothesis is to test whether the RED intervention plus the collaborative-care approach for depression (RED-D) will reduce the all-cause 30 and 90 day hospital readmission rates for patients who screen positive for depressive symptoms
All-cause reutilization rates 30 & 90 days post discharge from index hospitalization The primary hypothesis is to test whether the RED intervention plus the collaborative-care approach for depression (RED-D) will reduce the all-cause 30 and 90 day hospital utilization rates for patients who screen positive for depressive symptoms
- Secondary Outcome Measures
Name Time Method cost-saving 90 & 180 after discharge from index hospitalization The economic analysis will investigate whether the two interventions are cost saving and whether the RED-D intervention is more cost saving than the RED intervention alone. The principal source of the savings is likely to be from reduced rehospitalizations within the 90 days of study follow-up. Hospital administrative records and insurance company data will be used to gather cost data. Additional costs of the two interventions will be estimated by costing staff time and other resources used. Cost-savings will be estimated by t-test comparisons of the mean costs for the groups; given randomization of patient assignment these will provide unbiased estimates.
Mental Health Related Quality of Life 30 days and 90 days after discharge from index admission The impact of the RED-D Collaborative Care Intervention mental health related quality of life will be ascertained using the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) and Work and Social Adjustment Scale (WSAS) . The investigators will test whether collaborative care for depression can produce a clinically meaningful improvement in mental health related quality of life compared to those patients receiving either usual care or the RED discharge alone.
Trial Locations
- Locations (1)
Boston Medical Center
🇺🇸Boston, Massachusetts, United States