EFFECT OF 2% LIGNOCAINE INJECTION ON PROPOFOL CONSUMPTION IN PATIENTS UNDERGOING COLONOSCOPY

Not yet recruiting

• Conditions: Diseases of the digestive system,

• Registration Number: CTRI/2023/03/050700
• Lead Sponsor: Dr Freeda Praveena Cutinha

Brief Summary

- This study aims at evaluating whether Intravenous 2% Lignocaine Hydrochloride administration can reduce Propofol dose requirement, and pain reduction on injection of propofol.

- To study the effect of 2% Intravenous Lignocaine Hydrochloride with Propofol in preserving hemodynamic and respiratory normality.

- To compare the ease ofprocedure for endoscopists and patient satisfaction and comfort during theprocedure

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-04
• Last Update Posted: 2023-03-13

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Adults aged more than 20 years and less than 60 years.
• Patients with American Society of Anaesthesiolgists(ASA I and II).
• Patients scheduled for colonoscopy.
• Time for the procedure fewer than 45 mins.

Exclusion Criteria

• Age less than 20 years and more than 60 years.
• American society of Anaesthesiologists(ASA) III and above.
• Procedure time more than 45 minutes.
• Pregnancy and Lactation.
• Pre-existing hypoxemia( Pulse oximetry SpO2<90%) Hypotension (Systolic blood pressure <90mmHg) Bradycardia(Heart rate<50beats/minute) Uncontrolled Hypertension(Systolic blood pressure >170mmHg, Diastolic blood pressure >100 mmHg) Respiratory Insufficiency.
• Severe Renal or Liver Failure.
• Allergy to Lignocaine.
• Atrioventricular block.
• Neuropsychiatric disorders using sedative hypnotics.
• Analgesics >3 months .
• Previous colectomy.
• Hyperalgesia or Refractory cancer pain.
• Intravenous anesthesia contraindication.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recovery time.	During induction | After induction | 1 min | 3 mins | 5 mins | 10 mins | 15 mins | 20 mins | 25 mins | 30 mins | 35 mins | 40 mins | 45 mins | At the end of procedure | At the time of recovery | 1 hour | 2 hour
Induction Dose of Propofol for the Procedure.	During induction | After induction | 1 min | 3 mins | 5 mins | 10 mins | 15 mins | 20 mins | 25 mins | 30 mins | 35 mins | 40 mins | 45 mins | At the end of procedure | At the time of recovery | 1 hour | 2 hour
Maintenance Dose of Propofol for the Procedure.	During induction | After induction | 1 min | 3 mins | 5 mins | 10 mins | 15 mins | 20 mins | 25 mins | 30 mins | 35 mins | 40 mins | 45 mins | At the end of procedure | At the time of recovery | 1 hour | 2 hour
Total amount of Propofol administered during the procedure.	During induction | After induction | 1 min | 3 mins | 5 mins | 10 mins | 15 mins | 20 mins | 25 mins | 30 mins | 35 mins | 40 mins | 45 mins | At the end of procedure | At the time of recovery | 1 hour | 2 hour
Induction time.	During induction | After induction | 1 min | 3 mins | 5 mins | 10 mins | 15 mins | 20 mins | 25 mins | 30 mins | 35 mins | 40 mins | 45 mins | At the end of procedure | At the time of recovery | 1 hour | 2 hour

Secondary Outcome Measures

Name	Time	Method
1. Intra Operative Hemodynamic Variables.	-Heart Rate (HR).

Trial Locations

Locations (1)

Kasturba Medical College Hospitals.; 🇮🇳 Kannada, KARNATAKA, India

Kasturba Medical College Hospitals.

🇮🇳Kannada, KARNATAKA, India

Dr Freeda Praveena Cutinha

Principal investigator

8197967512

freeda810@gmail.com