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Establishing the Collaborative Care Model for Pediatric Allergic Rhinitis With Sleep Disorder

Not Applicable
Completed
Conditions
Allergic Rhinitis
Sleep Disorder
Interventions
Other: TCM
Other: Western medicine
Registration Number
NCT05031793
Lead Sponsor
China Medical University Hospital
Brief Summary

The purpose of study is to compared the impact of the integrative care clinic to ordinary western medicine among patients of moderate persistent allergic rhinitis combined with sleep disorder and establishing the collaborative care model of TCM and western medicine for pediatric allergic rhinitis with sleep disorder.

Investigators invited children aged below 18 years old to the integrative care clinic as experimental group, who have persistent moderate allergic rhinitis, more than 60 scores of the OSA-18 sleep questionnaire, and can accept integrative therapy. The controlled group is patients who receive ordinary western treatment. Investigators compare these two groups by questionnaires of OSA-18,SN-5, PADQLQ,SNAP-IV, the dose of nasal corticosteroid , and polysomnography.

Detailed Description

In Taiwan, there are many patients suffer from pediatric allergic rhinitis and lead to the medical heavy budget. The persistent symptoms would cause sleep disorder or complicated with pediatric obstructive sleep apnea. It would affect the growth development ,attention deficiency, or psychiatric cognition problems. Obstructive sleep apnea for a long time would result in cardiovascular, endocrine, and metabolic complications if not well-treated.

Patients of allergic rhinitis combined with sleep disorder are classified to moderate persistent type by ARIA, who are intractable to ordinary treatment. Investigators invited them to the integrative care clinic. In addition to the ordinary western medicine, the therapies in the integrative care clinic included herbal medicine, nasal aerosol inhalation, acupuncture, and health care education. The purpose of our study is to compared the impact of the integrative care clinic to ordinary western medicine among patients of moderate persistent allergic rhinitis combined with sleep disorder and establishing the collaborative care model of TCM and western medicine for pediatric allergic rhinitis with sleep disorder.

Investigators invited children aged below 18 years old to the integrative care clinic as experimental group, who have persistent moderate allergic rhinitis, more than 60 scores of the OSA-18 sleep questionnaire, and can accept integrative therapy. The controlled group is patients who receive ordinary western treatment. Investigators compare these two groups by questionnaires of OSA-18,SN-5, PADQLQ,SNAP-IV, the dose of nasal corticosteroid , and polysomnography.

Investigators hoped to prove the effect of integrative care clinic and to upgrade the quality and efficacy of the treatment among persistent moderate allergic rhinitis children.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
35
Inclusion Criteria
  1. age <18 years old
  2. ARIA (2014) diagnostic criteria belong to moderate, persistent
  3. OSA-18 score ≥60
Exclusion Criteria
  1. cranial-facial anomaly
  2. secondary obstruction sleep apnea due to muscle weakness of upper airway, such as Down syndrome or cerebral palsy
  3. psychiatric disease or behavior disorder
  4. allergy to TCM or ordinary western medicine treatment
  5. asthma

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Collaborative Care of TCM and Western MedicineWestern medicine-
Western medicineWestern medicine-
Collaborative Care of TCM and Western MedicineTCM-
Primary Outcome Measures
NameTimeMethod
The change of SN-5 scoresweek 8

SN-5 questionnaire is a tool to evaluate quality of life of sinus and nasal symptoms

Secondary Outcome Measures
NameTimeMethod
dosage of intra-nasal corticosteroidweek 8

Weight change of intra-nasal corticosteroid before and after study

The change of scores of Pediatric allergic disease quality of life questionnaire (PADQLQ)week 8

Pediatric allergic disease quality of life questionnaire (PADQLQ) is a validated tool to evaluate quality of life of pediatric allergic disease.

The change of scores of questionnaire of pediatric obstructive sleep apnea (OSA-18)week 8

Obstructive Sleep Apnea-18

The change of scores of Pediatric Sleep Questionnaireweek 8

Pediatric Sleep Questionnaire is a validated questionnaire to evaluate sleep quality among children

Apnea-Hyponea indexweek 12

Apnea-Hyponea index is evaluated by polysomnography

The change of hyperactivity-inattentive conditionweek 8

SNAP-IV is a validated tool designed by Swanson, Nolan and Pelham ,is the questionnaire used to evaluate hyperactivity-inattentive condition .

Trial Locations

Locations (1)

China Medical University Hospital

🇨🇳

Taichung, Taiwan

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