Packing of Perianal Abscess Cavities Trial: A Randomised Multicentre Trial Comparing Packing With Non-packing of the Abscess Cavity
Not Applicable
- Conditions
- Perianal Abscess
- Interventions
- Other: Packing of abscess cavityOther: External dressing
- Registration Number
- NCT01739478
- Lead Sponsor
- North Western Research Collaborative
- Brief Summary
The aim of this study is to compare the effect of packing and non-packing on the healing rate of perianal abscess cavities. Secondary objectives are to assess quality of life, cost effectiveness and rate of abscess recurrence and fistula-in-ano formation. If there is no difference in time to healing and non-packing is shown to be safe, acceptable to the patient and cost effective, this approach may become more widely accepted.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
- Clinical diagnosis of acute primary perianal abscess
- Have undergone surgical incision and drainage as an emergency
Exclusion Criteria
- The abscess is the sequelae of concurrent disease or trauma
- Fourniers gangrene is suspected
- Unable to give informed consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Packing of abscess cavity Packing of abscess cavity Current practice Packing of abscess cavity External dressing Current practice Non-packing of abscess cavity External dressing -
- Primary Outcome Measures
Name Time Method Time to wound healing in days, defined as complete epithelialisation of the abscess cavity. 1 day to 6 weeks time to healing will be assessed in days
- Secondary Outcome Measures
Name Time Method Quality of life scores as determined by the Euro QoL EQ-5D-3L 10 to 14 days Quality of life scores as determined by the Euro QoL EQ-5D-3L will be measured at 10-14 days following incision and drainage of abscess