Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Phase 3

Active, not recruiting

• Conditions: Moderate-to-Severe Atopic Dermatitis
• Interventions: Drug: Nemolizumab

• Registration Number: NCT03989206
• Lead Sponsor: Galderma R&D

Brief Summary

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Detailed Description

Long-term study to assess the safety and efficacy of nemolizumab in subjects with moderate-to-severe AD

Study Timeline

• Study First Submitted: 2019-06-14
• Study First Submitted QC: 2019-06-14
• Study First Posted: 2019-06-18
• Study Start: 2019-12-30
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-29
• Last Update Posted: 2024-10-30
• Primary Completion: 2026-08-31
• Study Completion: 2026-08-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1700

Inclusion Criteria

1. Subjects who may benefit from study participation in the opinion of the investigator and had participated in a prior nemolizumab study for AD
2. Female subjects of childbearing potential (ie, fertile, following menarche and until becoming post-menopausal unless permanently sterile) must agree either to be strictly abstinent throughout the study and for 12 weeks after the last study drug injection, or to use an effective and approved method of contraception throughout the study and for 12 weeks after the last study drug injection.

Key

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Exclusion Criteria

1. Subjects who, during their participation in a prior nemolizumab study, experienced an AE which in the opinion of the investigator could indicate that continued treatment with nemolizumab may present an unreasonable risk for the subject.
2. Pregnant women, breastfeeding women, or women planning a pregnancy during the clinical study.
3. Body weight < 30 kg
4. Cutaneous infection within 1 week before the baseline visit, any infection requiring treatment with oral or parenteral antibiotics, antivirals, antiparasitics or antifungals within 2 weeks before the baseline visit, or any confirmed or suspected coronavirus disease (COVID)-19 infection within 2 weeks before the screening or baseline visit. Subjects may be rescreened once the infection has resolved. Resolution of COVID-19 infection can be confirmed by recovery assessment methods.
5. History of hypersensitivity (including anaphylaxis) to an immunoglobulin product (plasma-derived or recombinant, eg, monoclonal antibody)
6. Any clinically significant issue, based investigator judgement

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Nemolizumab	Nemolizumab	Nemolizumab administered via subcutaneous injection

Primary Outcome Measures

Name	Time	Method
Incidence of Serious TEAEs	Baseline to Week 200
Incidence and Severity of TEAEs	Baseline to Week 200
Incidence and Severity of Adverse Events of Special Interest (AESIs) Throughout the Study	Baseline to Week 200

Secondary Outcome Measures

Name	Time	Method
Change from Baseline in Dermatology Life Quality Index (DLQI)	Baseline to Week 200
Proportion of Participants with IGA score = 0-1 at Each Visit	Baseline to Week 200
Change and Percent Change From Baseline in Participant-Reported Pruritus Using 10-cm VAS (SCORAD Sub-Component)	Baseline to Week 200
Proportion of Participants Satisfied with Study Treatment Based on PGAT at each visit	Baseline to Week 200
Change From Baseline in Work Productivity and Activity Impairment: Atopic Dermatitis (WPAI:AD) for Each Subscale at Each Visit Through Week 200	Baseline to Week 200
Time to First Relapse	Baseline to Week 200
Change and Percent Change From Baseline in SCORAD Score at Each Visit	Baseline to Week 200
Proportion of Participants with EASI-75 at Each Visit	Baseline to Week 200
Proportion of Participants Receiving Any Rescue Therapy by Rescue Treatment Type at Any Visit During the Treatment Period	Baseline to Week 200
Proportion of Participants Reporting Low Disease Activity State Based on PGAD at Each Visit	Baseline to Week 200
Proportion of Participants with IGA ≤ 2 at Each Visit	Baseline to Week 200
Change From Baseline in Children's Dermatology Life Quality Index (cDLQI) Total Score at Each Visit Through Week 200	Baseline to Week 200
Change From Baseline in Patient-Oriented Eczema Measure (POEM) Total Score at Each Visit Through Week 200	Baseline to Week 200
Duration of Remission	Baseline to Week 200
Change and Percent Change From Baseline in Overall Eczema Area and Severity Index (EASI) Score at Each Visit	Baseline to Week 200	EASI assesses severity and extent of AD signs through a composite score of erythema, induration/population, excoriation, and lichenification. The severity will be assessed on a scale of 0 (absent) to 3 (severe) for each of the 4 body areas: head/neck, trunk, upper limbs, and lower limbs, with half points allowed. The EASI score can range from 0 to 72 with higher scores representing greater severity of atopic dermatitis.
Change and Percent Change From Baseline in Participant-Reported Sleep Loss Using 10-cm VAS (SCORAD Sub-Component)	Baseline to Week 200
Change From Baseline in Hospital Anxiety and Depression Scale (HADS) for Each Subscale at Each Visit Through Week 200	Baseline to Week 200
Change From Baseline in EuroQoL 5-Dimension (EQ-5D) at Each Visit Through Week 200	Baseline to Week 200
Time to Permanent Study Drug Discontinuation	Baseline to Week 200

Trial Locations

Locations (342)

Galderma Investigational Site 8206; 🇺🇸 Norman, Oklahoma, United States

Galderma Investigational Site 8737; 🇺🇸 Miami, Florida, United States

Galderma Investigational Site 8706; 🇺🇸 Miami, Florida, United States

Galderma Investigational Site 8692; 🇺🇸 San Diego, California, United States

Galderma Investigational Site 8658; 🇺🇸 San Diego, California, United States

Galderma Investigational Site 8825; 🇺🇸 Las Vegas, Nevada, United States

Galderma Investigational Site 8749; 🇺🇸 Birmingham, Alabama, United States

Galderma Investigational Site 8125; 🇺🇸 San Francisco, California, United States

Galderma Investigational Site 8672; 🇺🇸 Salt Lake City, Utah, United States

Galderma Investigational Site 8866; 🇺🇸 Guntersville, Alabama, United States

Galderma Investigational Site 8893; 🇺🇸 Birmingham, Alabama, United States

Galderma Investigational Site 8808; 🇺🇸 Scottsdale, Arizona, United States

Galderma Investigational Site 8880; 🇺🇸 North Little Rock, Arkansas, United States

Galderma Investigational Site 8831; 🇺🇸 Anaheim, California, United States

Galderma Investigational Site 8906; 🇺🇸 Bell Gardens, California, United States

Galderma Investigational Site 8456; 🇺🇸 Beverly Hills, California, United States

Galderma Investigational Site 8577; 🇺🇸 Encinitas, California, United States

Galderma Investigational Site 8636; 🇺🇸 Fountain Valley, California, United States

Galderma Investigational Site 8224; 🇺🇸 Fremont, California, United States

Galderma Investigational Site 8791; 🇺🇸 Fresno, California, United States

Galderma Investigational Site 8674; 🇺🇸 Los Angeles, California, United States

Galderma Investigational Site 8845; 🇺🇸 Huntington Beach, California, United States

Galderma Investigational Site 8888; 🇺🇸 Fullerton, California, United States

Galderma Investigational Site 8686; 🇺🇸 Lomita, California, United States

Galderma Investigational Site 8813; 🇺🇸 Los Angeles, California, United States

Galderma Investigational Site 8907; 🇺🇸 Newport Beach, California, United States

Galderma Investigational Site 8683; 🇺🇸 Los Angeles, California, United States

Galderma Investigational Site 8745; 🇺🇸 Pasadena, California, United States

Galderma Investigational Site 8671; 🇺🇸 San Diego, California, United States

Galderma Investigational Site 8799; 🇺🇸 Ontario, California, United States

Galderma Investigational Site 8536; 🇺🇸 Santa Ana, California, United States

Galderma Investigational Site 8805; 🇺🇸 Cape Coral, Florida, United States

Galderma Investigational Site 8870; 🇺🇸 Boca Raton, Florida, United States

Galderma Investigational Site 8804; 🇺🇸 Hialeah, Florida, United States

Galderma Investigational Site 8711; 🇺🇸 Jacksonville, Florida, United States

Galderma Investigational Site 8523; 🇺🇸 Largo, Florida, United States

Galderma Investigational Site 8806; 🇺🇸 Miami Lakes, Florida, United States

Galderma Investigational Site 8800; 🇺🇸 Miami Lakes, Florida, United States

Galderma Investigational Site 8719; 🇺🇸 Miami, Florida, United States

Galderma Investigational Site 8851; 🇺🇸 Miami, Florida, United States

Galderma Investigational Site 8656; 🇺🇸 Miami, Florida, United States

Galderma Investigational Site 8801; 🇺🇸 Miami, Florida, United States

Galderma Investigational Site 8734; 🇺🇸 Pembroke Pines, Florida, United States

Galderma Investigational Site 8708; 🇺🇸 Miami, Florida, United States

Galderma Investigational Site 8856; 🇺🇸 Ormond Beach, Florida, United States

Galderma Investigational Site 8667; 🇺🇸 Columbus, Georgia, United States

Galderma Investigational Site 8744; 🇺🇸 Macon, Georgia, United States

Galderma Investigational Site 8728; 🇺🇸 Newnan, Georgia, United States

Galderma Investigational Site 8707; 🇺🇸 Stockbridge, Georgia, United States

Galderma Investigational Site 8819; 🇺🇸 Nampa, Idaho, United States

Galderma Investigational Site 9916; 🇺🇸 Chicago, Illinois, United States

Galderma Investigational Sites 8571; 🇺🇸 Skokie, Illinois, United States

Galderma Investigational Site 8739; 🇺🇸 Normal, Illinois, United States

Galderma Investigational Site 8729; 🇺🇸 Rolling Meadows, Illinois, United States

Galderma Investigational Site 8712; 🇺🇸 Skokie, Illinois, United States

Galderma Investigational Site 8142; 🇺🇸 Indianapolis, Indiana, United States

Galderma Investigational Site 9934; 🇺🇸 Shawnee Mission, Kansas, United States

Galderma Investigational Site 8882; 🇺🇸 Bangor, Maine, United States

Galderma Investigational Site 8554; 🇺🇸 Detroit, Michigan, United States

Galderma Investigational Site 8617; 🇺🇸 Farmington Hills, Michigan, United States

Galderma Investigational Site 8849; 🇺🇸 Troy, Michigan, United States

Galderma Investigational Site 8226; 🇺🇸 Warren, Michigan, United States

Galderma Investigational Site 8810; 🇺🇸 Omaha, Nebraska, United States

Galderma Investigational Site 8521; 🇺🇸 Saint Joseph, Missouri, United States

Galderma Investigational Site 8718; 🇺🇸 Missoula, Montana, United States

Galderma Investigational Site 8242; 🇺🇸 Brooklyn, New York, United States

Galderma Investigational Site 8733; 🇺🇸 New York, New York, United States

Galderma Investigational Site 9925; 🇺🇸 Glendale, New York, United States

Galderma Investigational Site 8702; 🇺🇸 Bexley, Ohio, United States

Galderma Investigational Site 8620; 🇺🇸 New York, New York, United States

Galderma Investigational Site 8772; 🇺🇸 Durham, North Carolina, United States

Galderma Investigational Site 8795; 🇺🇸 Shelby, North Carolina, United States

Galderma Investigational Site 8747; 🇺🇸 Cincinnati, Ohio, United States

Galderma Investigational Site 8595; 🇺🇸 Dublin, Ohio, United States

Galderma Investigational Site 8255; 🇺🇸 Philadelphia, Pennsylvania, United States

Galderma Investigational Site 8721; 🇺🇸 Pittsburgh, Pennsylvania, United States

Galderma Investigational Site 8802; 🇺🇸 Plymouth Meeting, Pennsylvania, United States

Galderma Investigational Site 8713; 🇺🇸 North Charleston, South Carolina, United States

Galderma Investigational Site 8133; 🇺🇸 Arlington, Texas, United States

Galderma Investigational Site 8827; 🇺🇸 Dripping Springs, Texas, United States

Galderma Investigational Site 8245; 🇺🇸 Dallas, Texas, United States

Galderma Investigational Site 8807; 🇺🇸 Houston, Texas, United States

Galderma Investigational Site 8787; 🇺🇸 Plano, Texas, United States

Galderma Investigational Site 8042; 🇺🇸 Houston, Texas, United States

Galderma Investigational Site 8670; 🇺🇸 Houston, Texas, United States

Galderma Investigational Site 8738; 🇺🇸 Burke, Virginia, United States

Galderma Investigational Site 8862; 🇺🇸 Fairfax, Virginia, United States

Galderma Investigational Site 5759; 🇦🇺 Kogarah, New South Wales, Australia

Galderma Investigational Site 6159; 🇦🇺 Woodville, South Australia, Australia

Galderma Investigational Site 8434; 🇺🇸 Seattle, Washington, United States

Galderma Investigational Site 5638; 🇦🇺 Benowa, Queensland, Australia

Galderma Investigational Site 6131; 🇦🇺 Carlton, Victoria, Australia

Galderma Investigational Site 6152; 🇦🇺 Westmead, New South Wales, Australia

Galderma Investigational Site 6161; 🇦🇺 Brisbane, Queensland, Australia

Galderma Investigational Site 5458; 🇦🇺 Parkville, Victoria, Australia

Galderma Investigational Site 5366; 🇦🇺 East Melbourne, Victoria, Australia

Galderma Investigational Site 6160; 🇦🇺 Parkville, Victoria, Australia

Galderma Investigational Site 6157; 🇦🇹 Graz, Styria, Austria

Galderma Investigational Site 6153; 🇦🇺 Victoria Park, Western Australia, Australia

Galderma Investigational Site 6158; 🇦🇹 Vienna, Austria

Galderma Investigational Site 6194; 🇦🇹 Vienna, Austria

Galderma Investigational Site 6163; 🇧🇪 Edegem, Belgium

Galderma Investigational Site 6051; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6078; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6102; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6216; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6046; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6080; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 8085; 🇨🇦 Calgary, Alberta, Canada

Galderma Investigational Site 8903; 🇨🇦 Calgary, Alberta, Canada

Galderma Investigational Site 8215; 🇨🇦 Calgary, Alberta, Canada

Galderma Investigational Site 8161; 🇨🇦 Surrey, British Columbia, Canada

Galderma Investigational Site 8904; 🇨🇦 Guelph, Ontario, Canada

Galderma Investigational Site 8586; 🇨🇦 Barrie, Ontario, Canada

Galderma Investigational Site 8780; 🇨🇦 Niagara Falls, Ontario, Canada

Galderma Investigational Site 8610; 🇨🇦 Ottawa, Ontario, Canada

Galderma Investigational Site 8899; 🇨🇦 Toronto, Ontario, Canada

Galderma Investigational Site 8336; 🇨🇦 Toronto, Ontario, Canada

Galderma Investigational Site 8731; 🇨🇦 Waterloo, Ontario, Canada

Galderma Investigational Site 5225; 🇨🇿 Náchod, Czechia

Galderma Investigational Site 8000; 🇨🇦 Saint John, Canada

Galderma Investigational Site 6030; 🇨🇿 Olomouc, Czechia

Galderma Investigational Site 6021; 🇨🇿 Praha, Czechia

Galderma Investigational Site 6024; 🇨🇿 Prague, Czechia

Galderma Investigational Site 6068; 🇪🇪 Tallinn, Estonia

Galderma Investigational Site 6069; 🇪🇪 Tallinn, Estonia

Galderma Investigational Site 6240; 🇨🇿 Prague, Czechia

Galderma Investigational Site 6054; 🇨🇿 Praha, Czechia

Galderma Investigational Site 6067; 🇪🇪 Tartu, Estonia

Galderma Investigational Site 6025; 🇨🇿 Praha, Czechia

Galderma Investigational Site 6198; 🇫🇷 Le Mans, France

Galderma Investigational Site 5031; 🇫🇷 Lille, France

Galderma Investigational Site 6167; 🇫🇷 Nantes, France

Galderma Investigational Site 5140; 🇫🇷 Nice, France

Galderma Investigational Site 6170; 🇫🇷 Martigues, France

Galderma Investigational Site 6133; 🇫🇷 Paris, France

Galderma Investigational Site 6166; 🇫🇷 Paris, France

Galderma Investigational Site 5407; 🇫🇷 Pierre-Bénite, France

Galderma Investigational Site 6135; 🇫🇷 Quimper, France

Galderma Investigational Site 6197; 🇫🇷 Toulon, France

Galderma Investigational Site 6169; 🇫🇷 Toulouse, France

Galderma Investigational Site 6168; 🇫🇷 Valence, France

Galderma Investigational Site 6235; 🇬🇪 Tbilisi, Georgia

Galderma Investigational Site 6224; 🇬🇪 Tbilisi, Georgia

Galderma Investigational Site 6227; 🇬🇪 Tbilisi, Georgia

Galderma Investigational Site 6230; 🇬🇪 Tbilisi, Georgia

Galderma Investigational Site 5482; 🇩🇪 Aachen, Germany

Galderma Investigational Site 6236; 🇬🇪 Zugdidi, Georgia

Galderma Investigational Site 6061; 🇩🇪 Bielefeld, Germany

Galderma Investigational Site 6062; 🇩🇪 Halle, Germany

Galderma Investigational Site 6082; 🇩🇪 Bonn, Germany

Galderma Investigational Site 5368; 🇩🇪 Darmstadt, Germany

Galderma Investigational Site 6028; 🇩🇪 Dülmen, Germany

Galderma Investigational Site 6132; 🇩🇪 Dresden, Germany

Galderma Investigational Site 5442; 🇩🇪 Gera, Germany

Galderma Investigational Site 6031; 🇩🇪 Düsseldorf, Germany

Galderma Investigational Site 6150; 🇩🇪 Hamburg, Germany

Galderma Investigational Site 6081; 🇩🇪 Goettigen, Germany

Galderma Investigational Site 6041; 🇩🇪 Hamburg, Germany

Galderma Investigational Site 6146; 🇩🇪 Langenau, Germany

Galderma Investigational Site 5382; 🇩🇪 Munich, Germany

Galderma Investigational Site 5469; 🇩🇪 Heidelberg, Germany

Galderma Investigational Site 8212; 🇺🇸 Portland, Oregon, United States

Galderma Investigational Site 6086; 🇩🇪 Kiel, Germany

Galderma Investigational Site 6084; 🇩🇪 Mainz, Germany

Galderma Investigational Site 6039; 🇩🇪 Münster, Germany

Galderma Investigational Site 5918; 🇩🇪 Osnabrück, Germany

Galderma Investigational Site 6109; 🇩🇪 Stuttgart, Germany

Galderma Investigational Site 5567; 🇭🇺 Debrecen, Hungary

Galderma Investigational Site 6045; 🇮🇹 L'Aquila, Italy

Galderma Investigational Site 5513; 🇭🇺 Budapest, Hungary

Galderma Investigational Site 6147; 🇭🇺 Budapest, Hungary

Galderma Investigational Site 6214; 🇩🇪 Tuebingen, Germany

Galderma Investigational Site 6026; 🇭🇺 Debrecen, Hungary

Galderma Investigational Site 6254; 🇭🇺 Gyula, Hungary

Galderma Investigational Site 6053; 🇭🇺 Veszprem, Hungary

Galderma Investigational Site 6145; 🇮🇹 Bologna, Italy

Galderma Investigational Site 6177; 🇮🇹 Rome, Italy

Galderma Investigational Site 6049; 🇮🇹 Roma, Italy

Galderma Investigational Site 6155; 🇮🇹 Rozzano, Italy

Galderma Investigational Site 6175; 🇮🇹 Vicenza, Italy

Galderma Investigational Site 6100; 🇰🇷 Busan, Korea, Republic of

Galderma Investigational Site 6120; 🇰🇷 Incheon, Korea, Republic of

Galderma Investigational Site 6098; 🇰🇷 Gyeonggi-do, Korea, Republic of

Galderma Investigational Site 6095; 🇰🇷 Bucheon-Si, Korea, Republic of

Galderma Investigational Site 6154; 🇰🇷 Gyeonggi-Do, Korea, Republic of

Galderma Investigational Site 6138; 🇰🇷 Incheon, Korea, Republic of

Galderma Investigational Site 6105; 🇰🇷 Seoul, Korea, Republic of

Galderma Investigational Site 6116; 🇰🇷 Seoul, Korea, Republic of

Galderma Investigational Site 5659; 🇰🇷 Seoul, Korea, Republic of

Galderma Investigational Site 6093; 🇰🇷 Incheon, Korea, Republic of

Galderma Investigational Site 6129; 🇰🇷 Seoul, Korea, Republic of

Galderma Investigational Site 6103; 🇰🇷 Seoul, Korea, Republic of

Galderma Investigational Site 6056; 🇰🇷 Seoul, Korea, Republic of

Galderma Investigational Site 6059; 🇱🇻 Riga, Latvia

Galderma Investigational Site 6099; 🇰🇷 Seoul, Korea, Republic of

Galderma Investigational Site 6113; 🇱🇻 Liepaja, Latvia

Galderma Investigational Site 6060; 🇱🇻 Talsi, Latvia

Galderma Investigational Site 6134; 🇱🇻 Riga, Latvia

Galderma Investigational Site 6073; 🇱🇹 Vilnius, Lithuania

Galderma Investigational Site 6111; 🇱🇹 Kaunas, Lithuania

Galderma Investigational Site 6112; 🇱🇹 Vilnius, Lithuania

Galderma Investigational Site 6212; 🇳🇱 Groningen, Netherlands

Galderma Investigational Site 6108; 🇳🇱 Rotterdam, Netherlands

Galderma Investigational Site 6118; 🇳🇿 Wellington, New Zealand

Galderma Investigational Site 5773; 🇵🇱 Białystok, Poland

Galderma Investigational Site 6097; 🇵🇱 Chorzów, Poland

Galderma Investigational Site 6255; 🇵🇱 Czestochowa, Poland

Galderma Investigational Site 6075; 🇵🇱 Gdańsk, Poland

Galderma Investigational Site 6052; 🇵🇱 Kraków, Poland

Galderma Investigational Site 6071; 🇵🇱 Lublin, Poland

Galderma Investigational Site 5377; 🇵🇱 Nowa Sól, Poland

Galderma Investigational Site 6063; 🇵🇱 Olsztyn, Poland

Galderma Investigational Site 6237; 🇵🇱 Ostrowiec Świętokrzyski, Poland

Galderma Investigational Site 6127; 🇵🇱 Poznań, Poland

Galderma Investigational Site 5495; 🇵🇱 Rzeszów, Poland

Galderma Investigational Site 6223; 🇵🇱 Szczecin, Poland

Galderma Investigational Site 6122; 🇵🇱 Warszawa, Poland

Galderma Investigational Site 6242; 🇵🇱 Warszawa, Poland

Galderma Investigational Site 6096; 🇵🇱 Wrocław, Poland

Galderma Investigational Site 6064; 🇵🇱 Warszawa, Poland

Galderma Investigational Site 6047; 🇵🇱 Wrocław, Poland

Galderma Investigational Site 6185; 🇵🇱 Wrocław, Poland

Galderma Investigational Site 6222; 🇵🇱 Warszawa, Poland

Galderma Investigational Site 6245; 🇵🇱 Łódź, Poland

Galderma Investigational Site 6231; 🇵🇱 Łódź, Poland

Galderma Investigational Site 6124; 🇸🇬 Singapore, Singapore

Galderma Investigational Site 6037; 🇪🇸 Barcelona, Spain

Galderma Investigational Site 6057; 🇪🇸 Alicante, Spain

Galderma Investigational Site 6106; 🇪🇸 Las Palmas De Gran Canaria, Spain

Galderma Investigational Site 6035; 🇪🇸 Barcelona, Spain

Galderma Investigational Site 6190; 🇪🇸 Madrid, Spain

Galderma Investigational Site 5580; 🇪🇸 L'Hospitalet De Llobregat, Spain

Galderma Investigational Site 6058; 🇪🇸 Madrid, Spain

Galderma Investigational Site 5842; 🇪🇸 Madrid, Spain

Galderma Investigational Site 6036; 🇪🇸 Madrid, Spain

Galderma Investigational Site 6191; 🇪🇸 Pamplona, Spain

Galderma Investigational Site 5551; 🇪🇸 Madrid, Spain

Galderma Investigational Site 6186; 🇪🇸 Madrid, Spain

Galderma Investigational Site 6202; 🇬🇧 Barnsley, United Kingdom

Galderma Investigational Site 6207; 🇬🇧 Blackpool, United Kingdom

Galderma Investigational Site 6203; 🇬🇧 Cannock, United Kingdom

Galderma Investigational Site 6090; 🇬🇧 Dudley, United Kingdom

Galderma Investigational Site 6104; 🇬🇧 Glasgow, United Kingdom

Galderma Investigational Site 6204; 🇬🇧 Liverpool, United Kingdom

Galderma Investigational Site 6121; 🇬🇧 London, United Kingdom

Galderma Investigational Site 6205; 🇬🇧 Manchester, United Kingdom

Galderma Investigational Site 6110; 🇩🇪 Berlin, Germany

Galderma Investigational Site 6040; 🇩🇪 Hamburg, Germany

Galderma Investigational Site 8857; 🇺🇸 Oklahoma City, Oklahoma, United States

Galderma Investigational Site 8279; 🇺🇸 New York, New York, United States

Galderma Investigational Site 6119; 🇳🇿 Hamilton, New Zealand

Galderma Investigational Site 8155; 🇺🇸 Troy, Michigan, United States

Galderma Investigational Site 8512; 🇺🇸 Bay City, Michigan, United States

Galderma Investigational Site 8816; 🇺🇸 Tampa, Florida, United States

Galderma Investigational Site 8203; 🇺🇸 Tampa, Florida, United States

Galderma Investigational Site 8889; 🇺🇸 Tampa, Florida, United States

Galderma Investigational Site 8839; 🇺🇸 Tampa, Florida, United States

Galderma Investigational Site 8578; 🇺🇸 Cerritos, California, United States

Galderma Investigational Site 8833; 🇺🇸 Inglewood, California, United States

Galderma Investigational Site 8329; 🇺🇸 San Antonio, Texas, United States

Galderma Investigational Site 8618; 🇺🇸 Waco, Texas, United States

Galderma Investigational Site 8726; 🇺🇸 Wilmington, North Carolina, United States

Galderma Investigational Site 8902; 🇺🇸 Doral, Florida, United States

Galderma Investigational Site 8786; 🇺🇸 Clearwater, Florida, United States

Galderma Investigational Site 8391; 🇺🇸 Hialeah, Florida, United States

Galderma Investigational Site 8850; 🇺🇸 Margate, Florida, United States

Galderma Investigational Site 8836; 🇺🇸 Jacksonville, Florida, United States

Galderma Investigational Site 8648; 🇺🇸 Wilmington, North Carolina, United States

Galderma Investigational Site 8608; 🇺🇸 Santa Monica, California, United States

Galderma Investigational Site 8820; 🇺🇸 Westminster, California, United States

Galderma Investigational Site 8704; 🇺🇸 Miami, Florida, United States

Galderma Investigational Site 8126; 🇺🇸 West Palm Beach, Florida, United States

Galderma Investigational Site 8828; 🇺🇸 Forest Hills, New York, United States

Galderma Investigational Site 8675; 🇺🇸 Las Vegas, Nevada, United States

Galderma Investigational Site 8723; 🇺🇸 Cortland, New York, United States

Galderma Investigational Site 8664; 🇺🇸 Frisco, Texas, United States

Galderma Investigational Site 8238; 🇺🇸 Dallas, Texas, United States

Galderma Investigational Site 5441; 🇦🇺 Darlinghurst, New South Wales, Australia

Galderma Investigational Site 8901; 🇨🇦 Ottawa, Ontario, Canada

Galderma Investigational Site 6055; 🇨🇿 Brno, Czechia

Galderma Investigational Site 6234; 🇬🇪 Tbilisi, Georgia

Galderma Investigational Site 6022; 🇩🇪 Bad Bentheim, Germany

Galderma Investigational Site 5566; 🇩🇪 Augsburg, Germany

Galderma Investigational Site 6094; 🇰🇷 Seoul, Korea, Republic of

Galderma Investigational Site 6027; 🇳🇱 Utrecht, Netherlands

Galderma Investigational Site 5138; 🇵🇱 Gdańsk, Poland

Galderma Investigational Site 6243; 🇵🇱 Gdańsk, Poland

Galderma Investigational Site 6085; 🇵🇱 Poznań, Poland

Galderma Investigational Site 6130; 🇵🇱 Szczecin, Poland

Galderma Investigational Site 6208; 🇬🇧 Newcastle, United Kingdom

Galderma Investigational Site 6206; 🇬🇧 Stockton-on-Tees, United Kingdom

Galderma Investigational Site 8771; 🇺🇸 Louisville, Kentucky, United States

Galderma Investigational Site 8743; 🇺🇸 Ann Arbor, Michigan, United States

Galderma Investigational Site 8777; 🇺🇸 Charleston, South Carolina, United States

Galderma Investigational Site 8736; 🇺🇸 Charleston, South Carolina, United States

Galderma Investigational Site 6088; 🇵🇱 Rzeszów, Poland

Galderma Investigational Site 6126; 🇵🇱 Warsaw, Poland

Galderma Investigational Site 5707; 🇵🇱 Warsaw, Poland

Galderma Investigational Site 6077; 🇸🇬 Singapore, Singapore

Galderma Investigational Site 6228; 🇬🇪 Tbilisi, Georgia

Galderma Investigational Site 5362; 🇵🇱 Kraków, Poland

Galderma Investigational Site 5367; 🇵🇱 Lublin, Poland

Galderma Investigational Site 8818; 🇺🇸 Rapid City, South Dakota, United States

Galderma Investigational Site 8740; 🇺🇸 Henderson, Nevada, United States

Galderma Investigational Site 6136; 🇧🇬 Stara Zagora, Bulgaria

Galderma Investigational Site 6251; 🇧🇬 Stara Zagora, Bulgaria

Galderma Investigational Site 6244; 🇵🇱 Gdynia, Poland

Galderma Investigational Site 6065; 🇵🇱 Warszawa, Poland

Galderma Investigational Site 5570; 🇵🇱 Łódź, Poland

Galderma Investigational Site 5499; 🇸🇬 Singapore, Singapore

Galderma Investigational Site 5448; 🇧🇪 Brussels, Belgium

Galderma Investigational Site 6162; 🇧🇪 Liège, Belgium

Galderma Investigational Site 6029; 🇧🇬 Pleven, Bulgaria

Galderma Investigational Site 6250; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6087; 🇵🇱 Katowice, Poland

Galderma Investigational Site 8447; 🇺🇸 Fort Smith, Arkansas, United States

Galderma Investigational Site 8873; 🇺🇸 Scottsdale, Arizona, United States

Galderma Investigational Site 6038; 🇧🇪 Leuven, Vlaams-Brabant, Belgium

Galderma Investigational Site 6164; 🇧🇪 Gent, Belgium

Galderma Investigational Site 8109; 🇺🇸 Lebanon, New Hampshire, United States

Galderma Investigational Site 8506; 🇺🇸 Hackensack, New Jersey, United States

Galderma Investigational Site 8637; 🇺🇸 Farmington, Connecticut, United States

Galderma Investigational Site 6156; 🇦🇹 Linz, Oberoesterreich, Austria

Galderma Investigational Site 6165; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6101; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6079; 🇧🇬 Sofia, Bulgaria

Galderma Investigational Site 6238; 🇬🇪 Tbilisi, Georgia

Galderma Investigational Site 5021; 🇵🇱 Katowice, Poland

Galderma Investigational Site 5363; 🇵🇱 Łódź, Poland

Galderma Investigational Site 6048; 🇵🇱 Tarnow, Poland

Galderma Investigational Site 5005; 🇵🇱 Wrocław, Poland

Galderma Investigational Site 8298; 🇺🇸 Austin, Texas, United States

Galderma Investigational Site 8896; 🇺🇸 Richmond, Virginia, United States

Galderma Investigational Site 8826; 🇺🇸 Albuquerque, New Mexico, United States

Galderma Investigational Site 8824; 🇨🇦 Edmonton, Alberta, Canada

Galderma Investigational Site 8722; 🇨🇦 Edmonton, Alberta, Canada

Galderma Investigational Site 8741; 🇺🇸 Buffalo, New York, United States

Galderma Investigational Site 8748; 🇺🇸 Ypsilanti, Michigan, United States

Galderma Investigational Site 8003; 🇺🇸 Webster, Texas, United States

Galderma Investigational Site 8817; 🇺🇸 Katy, Texas, United States

Galderma Investigational Site 8724; 🇺🇸 New Albany, Indiana, United States