Efficacy and Safety of Biocellulose Sheet From Coconut Juice Containing Anti-hyperpigmentation Agent ("Biocellulose Mask", "Farhorm®") in Patients Receiving Laser Treatment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- The skin pigmentation immediately after laser therapy and after using biocellulose mask
研究概览
简要总结
The laser areas treated with biocellulose sheet from coconut juice containing anti-hyperpigmentation agent ("biocellulose mask", "Farhorm®") heal faster than vaseline ointment which is a standard treatment.
详细描述
Volar surface at upper arm (2X2 cm) on both sides were treated with semi ablative, 1,550 nm Erbium: glass fractional laser. Biocellulose sheet from coconut juice containing anti-hyperpigmentation agent ("biocellulose mask","Farhorm®")was applied for 20 min on one side and the other side was treated with vaseline ointment. The redness, skin hydration and skin pigmentation were evaluated at that area before laser, immediately after laser and after applying the treatment. These parameters were compared between treatment (area treated with Biocellulose sheet from coconut juice containing anti-hyperpigmentation agent, "biocellulose mask", "Farhorm®") and control (vaseline ointment).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 20-50 years old
- •No skin problem such as inflammation, fresh wounds
- •Not receive laser treatment during last 3 months
- •No history of smoking or alcohol drinking
- •No allergy to licorice extract, Vit C, Vit E, arbutin or stearyl glycyrrhetinate
- •Willing to participate in this study and can comply with study protocol
排除标准
- •Has history of hyperallergic reaction
- •Has wound(s) on face during last 4 weeks
- •Has history of eczema, psoriasis during last 6 months
- •Has laser treatment during last month
- •Use steroid, antibiotic, anti-inflammatory drugs or antihistamine during 3 days before recruiting
- •Had major surgery during last 12 months
- •Has history of cancer during last 12 months
- •Pregnant or lactation
结局指标
主要结局
The skin pigmentation immediately after laser therapy and after using biocellulose mask
时间窗: Change from immediately after laser treatment and 30 min after laser and treatment with mask
次要结局
未报告次要终点
研究者
Pornanong Aramwit, Pharm.D., Ph.D
Associate Professor
Chulalongkorn University