NCT00382551已完成早期 1 期
The Effect of Alcohol and Polyphenolic Compounds on Endothelial Function
适应症
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 49
- 试验地点
- 2
- 主要终点
- Changes in flow-mediated vasodilation after 2 weeks intervention compared with baseline
研究概览
简要总结
To study the effect of red wine, beer and fruit juice on endothelial function in patients with coronary Heart disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men or postmenopausal women with stable coronary heart disease
- •Coronary heart disease should be verified by coronary angiography with at least 50% stenosis in at least one coronary vessel.
排除标准
- •Patients with myocardial infarction within the last tree months
- •Persons with a present or earlier alcohol abuse
- •Persons with a present or earlier drug abuse
- •Person with malign disease
- •Persons, that we consider unsuitable to carry through the examines.
结局指标
主要结局
Changes in flow-mediated vasodilation after 2 weeks intervention compared with baseline
次要结局
- Lipid status after 2 weeks intervention compared with baseline
- Effects in Coagulation factors after 2 weeks intervention
- Effects on markers of inflammation after 2 weeks intervention
- Effects on markers of endothelial function after 2 weeks intervention
- Changes in the overall antioxidant activity in plasma after 2 weeks intervention
研究者
研究点 (2)
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