Partial Wave Spectroscopic Detection of Colon Cancer Risk

Completed

• Conditions: Ulcerative Colitis; Colon Cancer
• Interventions: Procedure: PWS Testing

• Registration Number: NCT01095432
• Lead Sponsor: University of Chicago

Brief Summary

The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS) in patients who will undergo a standard of care colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC).

Detailed Description

The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS)in patients who will undergo a colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC). PWS has been recently developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer. We believe that the PWS test will more accurately detect the risk of colon cancer.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2010-03
• Study First Submitted: 2010-03-24
• Study First Submitted QC: 2010-03-26
• Study First Posted: 2010-03-30
• Primary Completion: 2015-11
• Study Completion: 2015-11
• Status Verified: 2016-05
• Last Update Submitted: 2016-05-20
• Last Update Posted: 2016-05-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Patient must be 18 years old or older.
• Patient is already scheduled for a standard of care colonoscopy or flexible sigmoidoscopy.
• Patient has not received chemotherapy.
• History of ulcerative colitis.

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Exclusion Criteria

• Patient is unable to give informed consent..
• Patient has received chemo or radiation therapy within the past 3 months.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Main Study Group	PWS Testing	All subjects who are undergoing a standard of care colonoscopy for flexible sigmoidoscopy and have a history of UC and agree to participate will be in the main study group.

Primary Outcome Measures

Name	Time	Method
Study samples of rectal mucosa (the moist lining of the rectum) using PWS.	1 year	Samples will be collected and then shipped to Northwestern University for analysis using PWS. This is to assess accuracy of detecting the risk for colon cancer.

Trial Locations

Locations (1)

University of Chicago, DCAM; 🇺🇸 Chicago, Illinois, United States