Pain Science Education in patients with Chronic Knee Pain

Completed

Conditions: Osteoarthritis of knee, unspecified,

Registration Number: CTRI/2019/03/018261

Lead Sponsor: SOAHS Manipal Academy of Higher Education

Brief Summary: Osteoarthritis (OA) is the second most common chronic musculoskeletal problem. Chronic pain is a hallmark for OA knee pain, causes changes in the brain which are engaged with medial prefrontal limbic region resulting in both physical and psychological changes, the phenomenon of central sensitization plays a crucial role in subjects with chronic arthritic pain resulting from hypersensitivity of central nervous system. Current evidence provide strong support for pain neuroscience education which positively influences pain rating pain knowledge improving limitation of movement and fear avoidance behaviour .Majority of literature review suggest that both clinical identification and treatment of OA using pain neuroscience education in reducing pain intensity improving cognition,emotional and functional aspects is still insufficient.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 124

Inclusion Criteria

Individuals diagnosed with OA using American College of Rheumatology (ACR) guidelines that described OA based on clinical examination as knee pain in addition to 3 of the following 6 criteria: -more than 50 years of age -less than 30 minutes of morning stiffness -crepitus -bony tenderness -no enlargement, or an absence of palpable warmth -along with radiographic classification of OA knee by Kellegren and Lawrence.
Knee pain for more than 3 months Symptoms of hyperalgesia measured using two-point discrimination device vernier caliper NPRS > 3 on walking.

Exclusion Criteria

Systemic inflammatory arthritis Intra- articular corticosteriod injection within 6 months A history of hip or knee surgeries Individuals with associated neurological deficits Intention to start or currently participating in lower limb exercise programs.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
6- minute walk test, two- point discrimination using vernier caliper	Baseline, at the end of 8th week

Secondary Outcome Measures

Name	Time	Method
Numerical Pain rating Scale	Baseline, at the end of 8th week
Central Sensitization Inventory scale	Baseline, at the end of 8th week
Knee Injury and Osteoarthritis Outcome Survey (KOOS)	Baseline, at the end of 8th week
Pain Catastrophizing Scale (PCS)	Baseline, at the end of 8th week
Quantitative Sensory Testing - Pain Pressure Threshold	Baseline, at the end of 8th week

Trial Locations

Locations (1): Manipal Hospital
🇮🇳
Bangalore, KARNATAKA, India
Manipal Hospital
🇮🇳Bangalore, KARNATAKA, India
Akhila Kandukuri
Principal investigator
8500447571
akhi.kandukuri9196@gmail.com