跳至主要内容
临床试验/NCT03139786
NCT03139786招募中不适用

Prospective Follow-up of a Cohort of Patients With Aortic Valve Bicuspidia: Multicentre Study

Centre Hospitalier Universitaire, Amiens1 个研究点 分布在 1 个国家目标入组 232 人开始时间: 2011年10月14日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
232
试验地点
1
主要终点
Analysis of 10 year mortality in cardiac surgery in a patient with bicuspid

研究概览

简要总结

The aortic valve bicuspidia (BVA) is a congenital condition corresponding to the presence of 2 sigmoids instead of 3. This is the most common cardiac congenital anomaly affecting 0.5 to 2% of the population The general rule. BVA may be associated with structural damage to the ascending aorta, which exposes BVA patients to a risk of developing ascending aortic aneurysm and acute aortic accidents. Recent data from the literature have revealed that the natural history of BVA is marked by a possible development towards significant valvulopathy and / or an ascending aortic aneurysm often requiring surgical treatment. However, the natural history of bicuspid disease remains poorly understood and the prognostic factors for progression to severe valvulopathy and / or aneurysmal dilatation of the ascending aorta remain to be determined.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients examined in the echocardiography laboratory whose objective examination was a bicuspid valve of the aortic valve
  • Bicuspidia may be formerly known

排除标准

  • Refusal to participate
  • Patients who had already undergone bicuspid surgery or ascending aorta before being examined at the echocardiography laboratory

结局指标

主要结局

Analysis of 10 year mortality in cardiac surgery in a patient with bicuspid

时间窗: 10 years

Analyzing the natural history of Bicuspidia

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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