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Clinical Trials/NCT05092906
NCT05092906
Completed
Not Applicable

Randomized Controlled Study Evaluating The Contribution of a Hypnosis Intervention During a Lumbar Puncture in the Neurology Department.

University Hospital, Grenoble1 site in 1 country74 target enrollmentNovember 9, 2021
ConditionsPain

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain
Sponsor
University Hospital, Grenoble
Enrollment
74
Locations
1
Primary Endpoint
Maximum pain felt during LP
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to assess the effect of hypnosis, as add on therapy, on patients requiring a lumbar puncture (LP) as part of their medical management.

Detailed Description

This study will follow the zelen's methodology randomization. It is an add-on study design. 1. The study will be presented to patients as an assessment of their comfort during the LP. The intervention group is not presented to the patient. 2. Patients are asked to sign the consent of the standard of care group. 3. Randomization into two equally sized groups: * Intervention arm : LP with complementary hypnoanalgesia * Control arm : LP without complementary hypnoanalgesia 4. Patients who have been randomized into the control group, will have LP according to the standard of care. Patients who have been randomized into the hypnoanalgesic group will be informed about the hypnoanalgesia intervention and then asked to sign the consent of the hypnosis group. * if the patient accepts, he will benefit from hypnosis during LP. * if the patient refuses, he will re-join the control group without hypnosis. The physicians performing LP will be the same in both groups. A phone call follow-up is scheduled on day 3 and 7 after intervention.

Registry
clinicaltrials.gov
Start Date
November 9, 2021
End Date
March 13, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital, Grenoble
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Required a lumbar puncture for diagnosis
  • Affiliated with social security system
  • Patient's written consent

Exclusion Criteria

  • LP contraindication
  • History of previous LP
  • Psychiatric disorder making the realization of a hypnosis irrelevant
  • Cognitive-behavioural abilities that do not allow the completion of the study
  • Persons who are protected under the act. Person deprived of liberty by judicial decision
  • Pregnant or Breastfeeding woman

Outcomes

Primary Outcomes

Maximum pain felt during LP

Time Frame: Immediately at the end of LP procedure

The maximum pain experienced will be assessed in the immediate post procedure using a Numeric Pain Rating Scale (NPRS). The NPRS is a 10 points scale, ranging from 0 (no pain) to 10 (maximal pain).

Secondary Outcomes

  • Ratio of patients with a Numeric Pain Rating Scale (NPRS) score >= 4.(Immediately at the end of LP procedure)
  • Comfort felt during LP(Immediately at the end of LP procedure)
  • Acceptation of hypnosis(Day1)
  • State and Trait anxiety before LP(Before randomization)
  • Assess pain at Day 3 and Day 7(Three days and then seven days after the LP.)
  • Timeframe for resumption of usual activities.(Seven days after the LP.)

Study Sites (1)

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