NCT00273416已完成2 期
A Randomized Double Blind, Placebo Controlled Balanced 4-Way Crossover Study To Assess The Efficacy Of Single Oral Doses Of PF-00592379 On Erectile Function, Using 100mg Sildenafil As A Positive Control
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- Pfizer
- 入组人数
- 32
- 试验地点
- 3
- 主要终点
- Duration of penile erections of greater than or equal to 60% rigidity as assessed by penile plethysmography (RigiScan PlusTM).
研究概览
简要总结
The primary aim of this study is to assess how effective PF-00592379 is in restoring penile erections in patients with erectile dysfunction. Patients will attend for 4 treatment visits where they will receive the following in random order; 2 separate doses of PF-00592379, sildenafil 100mg used as a positive control, or placebo (dummy medication). The effect on penile erections will be assessed in the clinic using penile plethysmography (RigiScan PlusTM technique).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Erectile dysfunction, previous good response to an oral treatment for erectile dysfunction.
排除标准
- •Patients with high blood pressure or certain heart conditions (e.g. angina, heart failure), regardless of whether treated or not.
- •Patients on nitrates or alpha-blocker medications.
结局指标
主要结局
Duration of penile erections of greater than or equal to 60% rigidity as assessed by penile plethysmography (RigiScan PlusTM).
次要结局
- Duration and quality of penile erections recorded in a self-assessment diary.
研究者
研究点 (3)
Loading locations...
相似试验
已完成
2 期
Study to Investigate Effect of a New Drug (PF-00446687) in Males Suffering From Erectile DysfunctionErectile DysfunctionNCT00862888Pfizer39
终止
不适用
Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical ProstatectomyErectile DysfunctionPenile CancerRadical ProstatectomyNCT00955929Memorial Sloan Kettering Cancer Center76
已完成
4 期
Investigate the Responsiveness of the Erectile Quality Scale to Vardenafil Flexible Dose vs Placebo in Males With Erectile Dysfunction (ED)Erectile DysfunctionNCT00665340Bayer219
已完成
2 期
A Study to Evaluate the Efficacy and Safety of Two Doses of PF-03654746 in Adults With Attention Deficit Hyperactivity Disorder (ADHD).Attention Deficit Hyperactivity DisorderNCT00531752Pfizer66
撤回
2 期
A Study Of Oral PF-01913539 In Patients With Mild To Moderate Alzheimer's DiseaseDementiaAlzheimer's DiseaseDimebonInvestigational DrugNCT01066481Pfizer