Use of the Boussignac CPAP System Immediately Following Extubation to Improve Lung Function in Adults With Moderate to Severe Obstructive Sleep Apnea
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obstructive Sleep Apnea (OSA)
- Sponsor
- Queen's University
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- percent forced vital capacity %(FVC)
- Status
- Terminated
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this study is to assess the efficacy of the Boussignac positive airway pressure system (a mask) applied immediately following post-operative extubation in improving lung function in patients with obstructive sleep apnea (OSA). Assessments will be done before surgery and then at 1, 2 and 24 hours following extubation and will be compared to standard care for perioperative airway support. The study aims to give a broader and more inclusive picture (than the current literature) in terms of whether the Boussignac CPAP system should be considered for utilization by anesthesiologists caring for surgical patients with OSA.
Investigators
Dr. Kim Turner
Principal Investigator
Queen's University
Eligibility Criteria
Inclusion Criteria
- •\> 18 years of age
- •ASA II-IV
- •Previous diagnosis of moderate to severe obstructive sleep apnea
- •diagnosed via polysomnography
- •BMI \< 40
- •scheduled for an abdominal or peripheral surgical procedure requiring endotracheal intubation and admission to hospital
Exclusion Criteria
- •BMI \> 40
- •Age \<18 years
- •inability to provide signed informed consent
- •intra-thoracic
- •head or neck surgery
- •contraindication for immediate post-extubation application of CPAP
- •not expected to be eligible for timely extubation following the surgical procedure
Outcomes
Primary Outcomes
percent forced vital capacity %(FVC)
Time Frame: 24 hours postoperatively
%FVC will be assessed 24 hours postoperatively in patients who received the Boussignac CPAP mask immediately post-extubation and these values compared to those of patients who received the standard-of-care treatment for obstructive sleep apnea
Secondary Outcomes
- % forced expiratory volume in 1 second (FEV1)(1,2 and 24 hours post-operatively)