The predictive value of the acute effect of beclomethasone-dipropionate on an exercise-challenge test for the outcome of longterm treatment with beclomethasone-dipropionate in childhood asthma.

Phase 4

Recruiting

• Conditions: exercise induced bronchoconstriction; 10006436

• Registration Number: NL-OMON47635
• Lead Sponsor: Medisch Spectrum Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

- Age between 12-18 years
- Clinical history of asthma and exercise induced bronchoconstriction
- Ability to perform an exercise-challenge test
- Maximal FEV1 > 70% of predicted value

Exclusion Criteria

- Other pulmonary or cardiac illnesses
- Use of nasal or systemic or inhalation corticosteroids, antihistamines, cromoglycates, anticholinergics or leukotriene
antagonists in two weeks prior to or during the study
- Use of long acting bronchodilator agents 24 hours before testing
- Use of short acting bronchodilator agents 8 hours before testing
- Hospitalization due to asthma exacerbation in past month
- Other changes in asthma medication during treatment period
- Upper or lower respiratory tract infections during treatment period
- Severe EIB i.e. a fall of >=40% FEV1 in the first ECT, requiring an acute change in maintenance medication
(standard care)
- Insufficient knowledge of the Dutch language

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Correlation between the difference in fall in FEV1 after a single dose of Qvar<br /><br>and after 4 weeks of treatment with Qvar.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>na</p><br>