KCT0002631已完成未知
Diagnostic accuracy of physical examinations to detect acute vertebral fragility fracture
Chung-Ang Univerisity Hospital0 个研究点目标入组 179 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 179
研究概览
简要总结
- Demographics A total of 179 patients were enrolled in our study and divided into the fracture group (n = 106) and the non-fracture group (n = 73). The mean age of the patients was 73.96 years (95% CI: 72.84-75.08), of which 35 were men and 144 were women. Demographic data including age, height, weight, BMI, and BMD (lumbar, femur neck, and hip total) demonstrated no significant differences between fracture and non-fracture groups. Seventy-four patients were evaluated for the presence of acute VFF with serial radiograph, 23 patients with CT, and 82 patients with MRI. 2. Diagnostic values of physical examinations FB-SU test demonstrated the most superior diagnostic value compared to other physical examinations with a sensitivity of 90.6%, specificity of 71.2%, and accuracy of 82.7%. Plain radiographic interpretation of acute VFF with clinical symptoms by two raters also had diagnostic value with sensitivity of 68.9%, specificity of 71.9%, and accuracy of 70.12%, thereby underperforming against the accuracy of FB-SU by more than 10%. Other physical examinations including BB-SU, SIT, FB-SI, BB-SI, STAND, SIT-STRAND, and WALK demonstrated extremely low sensitivity values ranging from 14.2% to 37.7% and in contrast, showed higher specificity values ranging from 87.7% to 100%. In case of tenderness, which is the physical examination most frequently performed in clinics, values of sensitivity, specificity, and accuracy were 45.3%, 75.3%, and 57.5% respectively. The McNemar test revealed that only FB-SU and plain radiographic interpretations by the rater 2 demonstrated significant diagnostic values (p > 0.025) compared to confirmatory results. Additional the McNemar test between physical examinations and plain radiographic interpretations by the rater 2 showed that FB-SU was a more valuable diagnostic tool with a higher sensitivity value of 90.6% than the latter’s 69.3%. No significant or minor adverse events occurred as a result of the suggested physical examinations.
研究设计
- 研究类型
- Observational Study
入排标准
- 年龄范围
- 60?(Year) 至 o Limit（—）
- 性别
- All
入选标准
- •Patients with acute back pain more than 60 years olds within 2 weeks
- •-Patients with low-energy injury compatible with criteria of fragility fracture, injury within own hieght
排除标准
- •-Patients with high-energy injury
- •-Patients without clinical and radiographic evaluation
- •-Patients having other medical diseases showing back pain
- •-Patients that disagreed with study and who are not fit for this study in judgment of the researchers
研究者
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